schrieb am 09.09.11 21:07:02
Erstaunliche Performance der Aktie in den letzten Tagen bei
grottenschlechter Marktstimmung. Hier wohl die Ursache:
September 8, 2011
Takeda Pharmaceutical Company Limited
SYR-472 Enters into Phase III Clinical Trials in Japan for the
Treatment of Type 2 Diabetes
Osaka, Japan, September 8, 2011 – Takeda Pharmaceutical Company
Limited (“Takeda”) announced that SYR-472 has entered into phase
III clinical trials in Japan to evaluate its safety and efficacy
for the treatment of type 2 diabetes.
Discovered by Takeda San Diego, Inc., a Takeda wholly-owned
subsidiary located in San Diego, California, SYR-472 is a
dipeptidyl peptidase-IV (DPP-4) inhibitor, which blocks DPP-4.
DPP-4 is an enzyme that selectively degrades two of the hormones
that increase insulin secretion, thereby increasing insulin
secretion and lowering blood glucose levels. SYR-472 is a
once-weekly oral formulation, expected to help control blood
glucose level as well as to improve medication compliance in
patients who receive treatment for type 2 diabetes.
Takeda is vigorously continuing its development activities to offer
a new treatment option to type 2 diabetes patients with a range of
clinical conditions.
(*)Glucagon-like peptide 1 (GLP-1) and glucose-dependent
insulinotropic peptide (GIP)
GLP-1 and GIP are secreted by the digestive tract following food
intake, and stimulate the beta cells in the pancreas—thereby
increasing insulin secretion—and they have the potential to improve
pancreatic beta-cell function. Furthermore, it is known that
because GLP-1 suppresses glucagon secretion from the pancreas, it
also has functions to suppress the production of sugar in liver
cells as well as to diminish appetite.
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