DBV Technologies Announces Publication of Positive Viaskin Peanut Data From NIAID-Sponsored Phase II Academic Study in the Journal of Allergy and Clinical Immunology

Press Release Montrouge, France, October 26, 2016

DBV Technologies Announces Publication of Positive Viaskin Peanut Data From NIAID-Sponsored Phase II Academic Study in the Journal of Allergy and Clinical Immunology

The study, CoFAR6, evaluated peanut-allergic patients 4 to 25 years of age

Primary endpoint of the study was met; greatest benefit observed in children

DBV Technologies (Euronext: DBV - ISIN: FR0010417345 - Nasdaq Stock Market: DBVT) today announced the publication of 12-month results from CoFAR6, a Consortium of Food Allergy Research (CoFAR) study sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), investigating the use of Viaskin Peanut for the treatment of peanut-allergic patients 4 to 25 years of age. The primary endpoint of the study, which measured a statistically significant desensitization to peanut, was met, with a greater clinical benefit reported in younger participants. The authors of the publication concluded that Viaskin Peanut was safe and could potentially be a convenient mode of treatment for peanut allergy.

Results from the CoFAR6 study were previously announced and presented at the 2016 American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting in March 2016 in Los Angeles, CA.

"No FDA-approved treatment for peanut allergy exists today. Risks of severe reactions from accidental exposure are a constant threat for these patients, even when following a peanut-free diet," said Dr. Stacie Jones, Professor of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR, and lead author of the publication. "A novel treatment that can provide an essential balance between safety and efficacy will be of key importance in the treatment of these patients. The results from CoFAR6 with Viaskin Peanut are promising, and we are looking forward to learning more about this new treatment modality." 

Viaskin Peanut is the company's lead product candidate, which is based on epicutaneous immunotherapy (EPIT), a proprietary technology platform that can deliver biologically active compounds to the immune system through the skin.

The CoFAR6 study publication, titled Epicutaneous Immunotherapy for the Treatment of Peanut Allergy in Children and Young Adults, was published online ahead of print in the Journal of Allergy and Clinical Immunology (JACI): www.jacionline.org/inpress (DOI: 10.1016/j.jaci.2016.08.017).