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Millennium Predictive Medicine and BD Enter Into Licensing Agreement In The Area of Colon Cancer Diagnostics

MILLENNIUM PHARMACEUTICALS, INC. LOGO
Millennium Pharmaceuticals, Inc. logo. (PRNewsFoto)[DM]
CAMBRIDGE, MA USA 12/20/1999



- New Agreement in Oncology Reflects Success of Existing Alliance -

CAMBRIDGE, Mass., July 18 /PRNewswire/ -- Millennium Predictive Medicine,
Inc. (MPMx), a wholly-owned subsidiary of Millennium Pharmaceuticals, Inc.
(Nasdaq: MLNM) today announced they have entered into a licensing agreement
with BD (Becton Dickinson and Company) (NYSE: BDX) in the area of colon cancer
diagnostics. Under the terms of the agreement, BD has paid MPMx a licensing
fee in exchange for certain research and development rights to select
diagnostic markers and related intellectual property developed by MPMx in this
disease area. BD also has an option to exercise a commercial license in the
future. The goal of this agreement is to identify markers that will
ultimately form the basis for new Diagnomic(TM) tests for colon cancer.
Diagnomic(TM) tests are molecular diagnostics that can describe a patient`s
current medical condition and provide prognostic and therapeutic information.
(Photo: http://www.newscom.com/cgi-bin/prnh/19991220/MLNMLOGO )
"Together, MPMx and BD have made the industry`s largest commitment to the
development of Diagnomic(TM) products in oncology. We are pleased to be
including colon cancer in the areas of cancer for which Diagnomic(TM) tests
will potentially be developed," said Kenneth Conway, president of Millennium
Predictive Medicine. "Diagnomic(TM) tests may play an important role in
combating colon cancer because of the tremendous value of early detection of
this disease."
"We have established a strong relationship with MPMx and are delighted to
add a further opportunity to address an area of critical unmet medical need,"
said Caroline Popper, M.D., M.P.H., General Manager, BD. "We look forward to
working with MPMx`s assets in the field of colon cancer and potentially moving
forward to develop novel diagnostic tests."

Colon Cancer
According to the American Cancer Society, about 93,800 new cases of colon
cancer will be diagnosed in the United States this year, and colon cancer will
cause 47,700 deaths. Nine out of ten people whose colorectal cancer is found
and treated at an early stage live at least five years. Like all other
cancers, colon cancer causes cells in the body to change and multiply beyond
normal ranges.
The exact cause of colon cancer is not yet known, but scientists have
identified certain risk factors, including family history of the disease,
smoking, a personal history of inflammatory bowel disease, obesity, inactivity
and age. The public`s reluctance to undergo screening tests is currently a
significant barrier to early disease identification.

Previously Existing Alliance
In February 1999, MPMx entered into a strategic alliance in the
diagnostics field with BD. The five-year, genomics-based research
collaboration focuses on the following areas of oncology: melanoma, cervical,
breast, ovarian, uterine and prostate. MPMx will supply clinically-validated
markers to BD and the two companies will jointly determine which tests, from
among staging, screening and pharmacogenomics, will be developed for each type
of cancer included in the alliance.
BD, a global medical technology company, headquartered in Franklin Lakes,
New Jersey, manufactures and sells a broad range of medical supplies and
devices and diagnostics systems for use by healthcare professionals, medical
research institutions, industry and the general public.
MPMx, a wholly-owned subsidiary of Millennium Pharmaceuticals, Inc., is
focused on the development of Diagnomic? and pharmacogenomic products and
services. MPMx is headquartered in Cambridge, Massachusetts.
Millennium, a leading biopharmaceutical company, applies its comprehensive
and integrated science and technology platform for the discovery and
development of breakthrough therapeutic and predictive medicine products, with
a goal of delivering personalized medicine. Through the industrialization of
this gene-to-patient platform, Millennium is also striving to accelerate the
process of drug discovery and development. Headquartered in Cambridge,
Massachusetts, Millennium and its affiliates currently employ more than 1,000
people.
This press release contains "forward-looking statements." These
statements include descriptions of Millennium`s operational plans,
expectations about future earnings and other results of operations, views of
future industry or market conditions, and other statements that include words
like "may," "expects," "believes," and "intends," and that describe opinions
about future events. Known and unknown risks may cause Millennium`s actual
results and performances to be materially different from those expressed or
implied by these statements. Some of these risks are: uncertainties relating
to unanticipated difficulties and delays relating to gene identification, drug
discovery and clinical development processes; changes in relationships with
strategic partners and dependence upon strategic partners for the performance
of critical activities under collaborative agreements; the impact of
competitive products and technological changes; uncertainties relating to
patent protection and regulatory approval; and uncertainties relating to the
ability of Millennium and its affiliates to obtain substantial additional
funds required for progress in drug discovery and development. These and other
factors are identified and more fully explained under the heading "Risk
Factors That May Affect Results" in the annual report on Form 10-K filed by
Millennium with the Securities and Exchange Commission on February 25, 2000.


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Autor (Datum des Eintrages): luna2000  (19.07.00 22:06:20)
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