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[posting]40762102[/posting]21.12.2010 19:35
Xoma shares soar on diabetes drug data hopes

BANGALORE, Dec 21 (Reuters) - Shares of biotechnology company Xoma Ltd jumped 50 percent on Tuesday on hopes of positive mid-stage data from its experimental diabetes drug.

Xoma is expected to report data from two mid-stage trials of its diabetes drug XOMA052 in early 2011, which could help the company in securing a partnership for the drug.

'With Phase II data on XOMA052 in diabetes expected in H1:11 we see an opportunity for meaningful near-term appreciation,' said Summer Street Research Partners analyst Bart Classen.

XOMAO52 works by blocking an inflammation-causing protein called Interleukin-1, which damages and destroy insulin-producing islet cells.

'We believe anti-IL-1 therapy could play an important role in diabetes due to its impact on islet cell function which could allow glucose control with a reduced risk of hypoglycemia or heart attacks,' Classen said.

The analyst said data from the mid-stage trials could confirm XOMA052's potential to become a blockbuster drug.

The Berkeley, California-based company's shares, which have lost three-fourth of their value in the last one year, were up 38 percent at $3.28 on Tuesday on Nasdaq.

More than 5.4 million shares changed hands, which was more than 19 times the stock's ten-day average volumes. (Reporting by Anand Basu in Bangalore; Editing by Vyas Mohan) Keywords: XOMA/SHARES

(anand.basu@thomsonreuters.com; within U.S. +1 646 223 8780; outside U.S. +91 80 4135 5800; Reuters Messaging:anand.basu.reuters.com@reuters.net)

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