BerGenBio to Present Interim Clinical and Biomarker Data From Phase II Development Programme With Selective AXL Inhibitor Bemcentinib at ASCO
- Four peer reviewed BerGenBio abstracts on clinical data with bemcentinib accepted for presentation at ASCO
- BerGenBio to host KOL reception to showcase bemcentinib studies and potential as a cornerstone of cancer therapy
BERGEN, Norway, 16, May 2018 /PRNewswire/ -- BerGenBio ASA (OSE: BGBIO) announces that the company and its collaborators will present new interim clinical and biomarker data from its extensive Phase II clinical development programme with bemcentinib, a selective, oral AXL inhibitor, at the 2018 annual meeting of the American Society of Clinical Oncology (ASCO) at McCormick Place in Chicago, IL (1-5 June 2018). Abstracts are now available online at https://am.asco.org/ and details of the presentations are below. The posters presented at ASCO will be made available on www.bergenbio.com in the Investors / Presentations section following the sessions.
Presentations at ASCO
Monday 4 June, 8:00 AM - 11:30 AM Central Daylight Time (Hall A)
Phase II open-label, multi-centre study of bemcentinib (BGB324), a first-in-class selective AXL inhibitor, in combination with pembrolizumab in patients with advanced NSCLC.
- James Lorens, PhD et al
- Session: Developmental Therapeutics – Immunotherapy
- Poster Board: #292, Abstract 3078
Identification of predictive and pharmacodynamic biomarkers associated with the first-in-class selective AXL inhibitor bemcentinib across multiple Phase II clinical trials.
- Robert J Holt, PhD et al
- Session: Developmental Therapeutics – Clinical Pharmacology and Experimental Therapeutics
- Poster Board: #385, Abstract 2559
Analysis of anti-leukemic activity, predictive biomarker candidates, immune activation and pharmakodynamics in R/R AML and MDS in response to treatment with bemcentinib (BGB324), a first-in class selective AXL inhibitor, in a Phase II open-label, multi-centre study.
- Bjørn T. Gjertsen, MD, PhD et al
- Session: Hematologic Malignancies – Leukemia, Myelodysplastic Syndromes, and Allotransplant
- Poster Board: #80, Abstract 7020
- To be discussed at the Poster Discussion Session on Monday 4 June, 11:30 AM - 12:45 PM, at E450
Monday 4 June, 1:15 PM - 4:45 PM CDT (Hall A)
A randomized Phase Ib/II study of the selective small molecule AXL inhibitor bemcentinib (BGB324) in combination with either dabrafenib/trametinib or pembrolizumab in patients with metastatic melanoma.