Okayama University Research Early Gastric Cancer Endoscopic Diagnosis System Using Artificial Intelligence
OKAYAMA, Japan, July 15, 2019 /PRNewswire/ -- Researchers at Okayama University have developed an early gastric cancer endoscopic diagnosis system using artificial intelligence (AI). The details were presented at the Congress of the Japan Gastroenterological Endoscopy Society (JGES), May 31 – June 2, 2019, Tokyo.
According to data released in 2017 by Japan's Ministry of Health, Labor, gastric cancer ranks third in cancer deaths in Japan: second in men and fourth in women.
Treatment of early-stage gastric cancer includes endoscopic surgery (ESD), which can save the stomach, and surgical procedures that require gastrectomy.
However, although advances in endoscopic treatment technology has led to the early detection of gastric cancer, decisions on whether to use endoscopy treatment or surgery mainly depend on how deep the cancer has invaded the stomach wall. Furthermore, these decisions are made by careful examination of endoscopic images by experienced physicians. At present, there are many cases where endoscopic treatment is performed first where surgery would have been more appropriate and vice versa.
With this background, Professor Yoshiro Kawahara of the Graduate School of Medical and Dental Sciences, Okayama University, and colleagues have developed artificial intelligence (AI)-based endoscope for early detection of gastric cancer. These research results were presented at the 97th Congress of the Japan Gastroenterological Endoscopy Society (JGES), May 31 – June 2, 2019, Tokyo.
First the prototype of the system to obtain the depth of early gastric cancer was constructed with GoogLeNet to match purpose (metastatic learning) by using the image recognition ability of CNN (Convolutional Neural Network) published by Google on numerical analysis software MATLAB.
Next, the researchers used the ResNet, which is a 152-layer convolutional neural network, to conduct intramucosal endoscopic resection among patients treated for early gastric cancer at Okayama University Hospital.
Using endoscopic images of 100 cancers (M group) and 50 submucosal invasion cancers (SM-ESD group) and 50 submucosal invasion cancers (SM-OPE group) who had undergone surgery from the beginning, the researchers built the AI system and verified its diagnostic accuracy.
The diagnostic accuracy of intramucosal cancer by artificial intelligence diagnostic system was sensitivity 82.7%, specificity 63.0%, positive predictive value 69.1%, negative predictive rate 78.4% in image unit, and sensitivity 82.0% in case unit. The specificity was 71.0%, the positive predictive value was 73.9%, and the negative predictive value was 79.8%.