The contract manufacturing market for live biotherapeutics and microbiome products is estimated to be worth USD 300 million by 2030, growing at a CAGR of 46%, claims Roots Analysis

With over 85 microbiome-based, live biotherapeutic products under preclinical and clinical development, the demand for R&D and manufacturing services for such products is anticipated to increase beyond the capabilities of innovator companies alone

LONDON, Aug. 4, 2020 /PRNewswire/ -- Roots Analysis has announced the addition of "Live Biotherapeutic Products and Microbiome Contract Manufacturing Market, 2020-2030: Focus on Active Pharmaceutical Ingredients and Finished Dosage Forms, 2020-2030" report to its list of offerings.

Manufacturing live biotherapeutic products is both technically challenging and financially demanding; as a result, innovator firms are becoming increasingly reliant on contract service providers to access specialized facilities and optimize overall costs.

To order this 300+ page report, which features 140+ figures and 125+ tables, please visit this link 

Key Market Insights

Over 25 players claim to provide microbiome-based live biotherapeutics contract manufacturing 

More than 80% of the companies engaged in this domain are mid-sized and large firms; examples of firms established in 2019 include Arranta Bio and BacThera (a Lonza and Chr. Hansen joint venture). Further, nearly 50% of the CMOs have established the necessary expertise for handling both anaerobic and aerobic strains.

35+ manufacturing facilities focused on live biotherapeutics have been established worldwide

Majority (~55%) of the manufacturing facilities are located in Europe, followed by North America. Prominent manufacturing hubs in the Europe include (in decreasing order of number of manufacturing facilities) the UK, France, the Netherlands, Italy, Germany, Switzerland, and Sweden.

Approximately 88% of the total installed capacity is dedicated to commercial scale manufacturing 

Whereas, rest (~10%) of the capacity is being used for preclinical / clinical scale manufacturing of microbiome products. In addition, over 60% of the total current global, installed manufacturing capacity is installed in Europe.

Over 170 registered clinical trials involved the use of microbiome-based live biotherapeutics

Majority of these studies are being conducted at various hospitals / centers across the US. Examples of leading non-industry players include (in decreasing order of number of trials) University of California, National Institute of Allergy and Infectious Diseases, Radboud University, and The University of Texas Health Science Center.