AIM ImmunoTech Announces PLOS ONE’s Publication of New Data Analyses Showing Importance of Disease Duration on Ampligen’s Positive Role in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - Seite 2
Many survivors of the first SARS-CoV-1 epidemic in 2003 continued to report classic chronic fatigue-like symptoms after recovering from the acute illness. In fact, approximately 27% of survivors met the CDC criteria for chronic fatigue syndrome, which requires at least 6 months of symptoms (See: jamanetwork.com/fullarticle/415378). There is now increasing evidence that patients with COVID-19 — the disease caused by SARS-CoV-2 — can develop a similar, ME/CFS-like illness, which aligns with anecdotal accounts of ME/CFS symptoms commencing after flu-like syndromes (See: https://jamanetwork.com/fullarticle/2768351).
The findings in the PLOS ONE publication potentially carry special importance for survivors of COVID-19, many of whom report classic chronic fatigue-like symptoms long after recovering from the acute SARS-CoV-2 infection. These patients are commonly referred to as “Long Haulers” because of the persistence of these symptoms. They are also uniquely situated to potentially benefit from Ampligen as an early onset therapy for subjects who have recovered from acute COVID-19 only to come down with chronic fatigue-like symptoms.
AIM announced on October 6 the receipt of Institutional Review Board (IRB) approval to expand its AMP-511 Early Access Program for ME/CFS patients to also include Long Haulers in the clinical sites at Incline Village, Nev. at Lake Tahoe and Charlotte, N.C. The expansion is designed to test the hypothesis that if Ampligen is to have beneficial effects on Long Haulers, then it would likely need to be used earlier in the disease process rather than later. AIM filed a provisional patent application for the use of Ampligen for COVID-19-induced chronic fatigue in June of 2020 (See: AIM ImmunoTech PR June 11, 2020).
“More than 10 percent of persons who contract COVID-19 develop long term symptoms that are remarkably similar to persons with Chronic Fatigue Syndrome (also known as ME/CFS). So there may be thousands of individuals with CFS-like illness in the near future. Such ‘Long Haulers’ could prove to benefit from Ampligen therapy. Moreover, the recently released analyses published in PLOS ONE indicate that the potential benefit of Ampligen in patients with ME/CFS may depend on treatment earlier in the disease,” said Charles Lapp, MD, of the Hunter-Hopkins Center, PLLC. (See: https://jamanetwork.com/fullarticle/2768351)