Antimicrobial Technologies - IDTechEx Discusses How They Work - Seite 2

Preventing adhesion to surfaces

A tactic to combat bacteria and mold is to simply prevent adherence to surfaces. Bacteria and mold have the ability to form biofilm, a dense film-like structure containing and protecting millions of microorganisms. The first step to forming biofilm, is adherence to a surface. Antimicrobial companies have created surfaces that provide an unfavorable environment for adhesion, resulting in a microorganism that simply lives out the rest of its short life in peace without growing and forming problematic films.

Does the mechanism of action matter?

In short, yes!

There is a great concern amongst scientists that antimicrobials that kill microorganisms from within can contribute to the development of antibiotic resistant bacteria. Almost all organisms have a mechanism called an efflux pump that is responsible for removing toxic substances. Extensive exposure to low levels of toxins pressures microorganisms to develop and evolve more effective efflux pumps, which the microorganism can also use to pump out antibiotics.

As far, scientists have only managed to induce resistance to antimicrobial technologies in the laboratory, but it will become a possibility in the wild if antimicrobial technologies are used irresponsibly. Antibiotic resistance is deemed by the World Health Organization as one of the top 10 global public health threats facing humanity – without effective antibiotics, many routine conditions and medical procedures today will become a matter of life and death.

IDTechEx have analyzed over 100 companies in the antimicrobial technology market, many of which are developing technologies to circumvent the problem of antimicrobial resistance. For more information on the topic, please refer to www.IDTechEx.com/Antimicrobial, or for the full portfolio of Healthcare related research available from IDTechEx please visit www.IDTechEx.com/Research/Healthcare.  

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