Oncotelic Publishes SNO 27th Annual Meeting Presentation Materials

AGOURA HILLS, Calif., Nov. 30, 2022 (GLOBE NEWSWIRE) -- Oncotelic Therapeutics, Inc (OTCQB:OTLC) ("Oncotelic", the "Company" or "We"), a developer of treatments for rare and orphan indications, including Parkinson's Disease, PDAC, DIPG, and COVID-19, today announced the publication of the presentation materials from the Society for Neuro-Oncology (“SNO”) 27th Annual Meeting held in Tampa Bay, FL on November 16th-20th, 2022 on our website (www.oncotelic.com).

Abstract #DDEL-16: Delivery of OT-101 – TGF-β2 Antisense for the Treatment of Glioblastoma.
https://www.oncotelic.com/wp-content/uploads/2022/11/Trieu-DDEL-16-Del ...

Abstract #RTID-04: Clinical Potential of Targeting Transforming Growth Factor β2 with OT-101 for Post-Radiation Consolidation in Diffuse Intrinsic Pontine Glioma.
https://www.oncotelic.com/wp-content/uploads/2022/11/Uckun-RTID-04-Cli ...

“Pediatric DMG is a very aggressive brain tumor in children that has a dismal prognosis with a median overall survival (OS) of less than one year after standard radiation therapy. Therefore, there is an urgent need for therapeutic innovations for treatment of pediatric DMG,” explained Fatih Uckun, MD PhD, the Chief Medical Officer of Oncotelic. “The primary goal of our DIPG project will be to carefully evaluate in a stepwise manner the safety and tolerability as well as efficacy of OT-101 when it is administered directly into the CSF of pediatric patients with DMG. The protocol of a new Phase 1 study was recently submitted to the FDA. The protocol for another study we recently designed was presented at the SNO meeting.”

“The support and strong interest from the subject matter experts who visited our poster reaffirmed the clinical importance of our DIPG project and the urgency of the unmet medical need in this field,” stated Cynthia Lee, PhD, VP of Regulatory R&D of Oncotelic.

“Oncotelic’s participation during the Society of Neuro-Oncology Annual Meeting is absolutely critical in the Company’s efforts to further its clinical development of OT-101 in the setting of tumors, particularly of the CNS. During the four day conference I met with many of the world’s Key Opinion Leads (KOLs) who share our belief in the promise of treating patients with anti-TGF-β2 antisense oligodeoxynucleotides either as a monotherapy or in combination with various anti-tumor modalities which may include radiation, chemotherapy, checkpoint inhibitors or various immunotherapeutic agents. It was a confirmation of our confidence in the clinical promise of OT-101 in the clinic and ultimately benefit to patients.” said Dr. Anthony Maida, Chief Clinical Officer - Translational Medicine, Oncotelic.