Teitur Trophics Raises EUR 28M in Series A Financing to Advance the Development and Treatment for Neurodegenerative Diseases

• Financing co-led by Sunstone Life Science Ventures and Sound Bioventures with participation from Industrifonden, Innovestor's Life Science Fund and P53 Invest
• Discovery of a novel mechanism with the potential to prevent the death of neurons in neurodegenerative diseases
• First-in-Class, Lead drug candidate advances into clinical development in a Phase 1b study

AARHUS, Denmark, March 14, 2023 /PRNewswire/ -- Teitur Trophics ("Teitur"), a biotech company dedicated to developing new treatments for patients suffering from neurodegenerative diseases, today announces the completion of a €28M Series A financing. The financing was co-led by Sunstone Life Science Ventures and Sound Bioventures, with participation from new investors, Industrifonden, Innovestor's Life Science Fund and P53 Invest. The proceeds will enable Teitur to progress its lead drug candidate, TT-P34, from candidate selection into clinical development, including a Phase 1b clinical study in neurodegenerative diseases.

Teitur, a spin out from Aarhus University seeded by the BioInnovation Institute ("BII") in 2020, has developed a platform of first-in-class cyclic peptides with a novel mechanism that preserves neuronal function. The peptides have the potential to treat patients suffering from a broad range of neurodegenerative diseases. Lead drug candidate, TT-P34 is administered subcutaneously and has shown potent, brain specific effects in animal models for Huntington's Disease, Parkinson's Disease and Frontotemporal Dementia.

TT-P34 was developed from the sortilin-related Vps10p domain containing receptor ("SorCS2") receptor and acts by targeting the three major pathophysiological hallmarks of neurodegeneration: mitochondrial failure, lysosomal dysfunction, and loss of pro-survival signaling. TT-P34 uniquely restores energy homeostasis in brain cells, induces clearance of toxic protein aggregates, and promotes neurotrophic effects, thereby supporting neuronal cell survival in neurodegenerative diseases.

Simon Mølgaard, Chief Executive Officer of Teitur Trophics said: "We are very pleased to welcome Sound Bioventures, Industrifonden, Innovestor's Life Science Fund and P53 Invest to Teitur, who will join our existing investor, Sunstone Life Science Ventures. This investor syndicate creates a very strong and committed shareholder base with a track record of supporting successful next generation companies. The €28 million Series A investment further validates our vision for preserving neuronal function in the face of these devastating neurodegenerative disorders. The funding will allow us to take our first-in-class, lead drug candidate, TT-P34 from candidate selection into clinical development, while also advancing our novel pipeline of innovative, peptides. There is a pressing need for new therapies for neurodegenerative diseases which have a detrimental impact on millions of people's lives around the world, with serious implications for quality of life and life expectancy."