Idorsia continues to further the science of sleep and insomnia with new daridorexant data and analyses published at Sleep Europe 2024

Allschwil, Switzerland – September 17, 2024

Idorsia Ltd (SIX: IDIA) today announced that new data and analyses of daridorexant, Idorsia’s dual orexin receptor antagonist for the treatment of adults with chronic insomnia, will be presented at Sleep Europe 2024 – the 27th Congress of the European Sleep Research Society (ESRS), taking place in Seville, Spain, September 24–27, 2024.

The following posters will be presented:

• Lederer K, et al. Efficacy and safety of daridorexant in patients with chronic insomnia disorder and comorbid nocturia [P5021], Wednesday, Sep 25, 12:15 – 13:15 and 16:00 – 17:45.
• McCall WV, et al. Dose-response of daridorexant in insomnia disorder: a meta-analysis of Phase 2 and 3 studies [P298], Wednesday, Sep 25, 12:15 – 13:15 and 16:00 – 17:45.
• Dauvilliers Y, et al. Effect of daridorexant on wakefulness throughout the night and morning sleepiness in patients with insomnia disorder [P1213], Friday, Sep 27, 10:45 – 13:30.
• Boof M-L, et al. Repeated dosing of 50 mg daridorexant in patients with severe obstructive sleep apnea: Effect on sleep-disordered breathing and sleep [P1200], Friday, Sep 27, 10:45 – 13:30.
• Muehlan C, et al. Nighttime Safety of Daridorexant: Response to Noise Stimuli, and effects on Postural Stability, Walking and Memory [P1197], Friday, Sep 27, 10:45 – 13:30.
• Kaufmann P, et al. Excretion of the Dual Orexin Receptor Antagonist Daridorexant into Breast Milk of Healthy Lactating Women [P1196], Friday, Sep 27, 10:45 – 13:30.
• Di Marco T, et al. Effect of daridorexant on sleep micro-architecture in adult patients with insomnia disorder – A post-hoc analysis of two pooled Phase 3 studies [P1198], Friday, Sep 27, 10:45 – 13:30.
• Lettieri CJ, et al. Effect of Daridorexant on Patients with Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnea: A Post-hoc Analysis of a Phase 3 Study [P1201], Friday, Sep 27, 10:45 – 13:30.

The abstracts can be found on the congress website.

In addition, Idorsia is supporting a satellite symposium entitled "Overactive wake-signaling and the management of insomnia disorder" on Thursday, September 26, from 12:15-13:15 CEST in Room “Paris 2”. The symposium will be hosted by Diego Garcia-Borreguero (Spain), Yves Dauvilliers (France), Laura Palagini (Italy), and Christina Lang (Germany), and will explore the latest standard of care for patients with chronic insomnia.