Cosmo to Unveil First-of-its-Kind Clinical Study on the Use of GI Genius(TM) with Apple Vision Pro at Rush University Medical Center

Dublin, Ireland--(Newsfile Corp. - June 24, 2025) - Cosmo Pharmaceuticals N.V. (“Cosmo”) today announced that in July 2025, it will initiate their first usability study of a medical device software application connecting the Medtronic GI Genius™ intelligent endoscopy module, an AI-powered platform for gastrointestinal endoscopy, with Apple Vision Pro. The study, to be conducted at Rush University Medical Center in Chicago under the leadership of Irving Waxman, MD, James R. Lowenstine Professor and Chief, Division of Digestive Diseases & Nutrition, and will evaluate the real-time use of this innovative technology during live colonoscopy procedures.

The software application – designed by Cosmo for use with Apple Vision Pro – will enable physicians to visualize AI-generated insights from the GI Genius™ module directly through Apple Vision Pro, enabling physicians to view important information without looking away from the operative screen. This innovative, spatial experience is being investigated for the first time in GI endoscopy and is believed to set the foundation for a new standard in procedural medicine. The GI Genius™ system uses artificial intelligence to increase the adenoma detection rate (ADR) of colorectal polyps by as much as 14.4%.

This innovation was made possible through extensive development work with spatial computing technology, utilizing Apple Vision Pro’s software architecture, input, and high-resolution display system. Cosmo’s teams engineered the software application to operate natively on Apple Vision Pro, unlocking a fusion of clinical AI experiences and spatial computing visualization never before seen in endoscopy.

The upcoming usability study – the first of its kind and conducted on patients undergoing routine colonoscopy – will serve as a key component of Cosmo’s planned FDA submission, expected shortly after the study concludes.

“We are thrilled to be the first in the world to evaluate this technology in the endoscopy suite,” said Prof. Irving Waxman. “What Cosmo has built by connecting the GI Genius™ module with Apple Vision Pro is extraordinary. It has the potential to revolutionize how we practice – by giving us AI-powered insights exactly when and where we need them. This is not just an incremental improvement – it’s a complete reimagining of procedural medicine, and I’m proud that Rush is leading the way.”