Abivax Announces Late-Breaking Presentation of 8-Week ABTECT Trial Results with Updated Safety Data

EQS-News: ABIVAX / Key word(s): Conference/Study results Abivax Announces Late-Breaking Presentation of 8-Week ABTECT Trial Results with Updated Safety Data 05.10.2025 / 17:00 CET/CEST The issuer is solely responsible for the content of this announcement. Abivax Announces Late-Breaking Presentation of 8-Week ABTECT Trial Results with Updated Safety Data

• 50 mg once-daily dose of obefazimod led to a pooled 16.4% (p<0.0001) placebo-adjusted clinical remission rate at Week 8; met primary and all key secondary endpoints in both ABTECT 1 and ABTECT 2 
• ABTECT trials enrolled refractory patient population with 47% of participants having prior inadequate response to advanced therapy, among whom 21% had prior inadequate response to JAK inhibitor therapy 
• Obefazimod treatment was well tolerated with no new safety signals identified for both the 25mg and 50mg doses
• Abivax to present a second late-breaking abstract on October 6. Management to host a conference call to discuss results of both late-breaking abstracts at 9am ET / 3pm CET on October 6.
   

PARIS, France – October 05, 2025 – 5:00 PM CET – Abivax SA (Euronext Paris: FR0012333284 – ABVX / Nasdaq: ABVX) (“Abivax” or the “Company”), a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases, today announced results from the first of two late-breaking presentations at the United European Gastroenterology (UEG) Meeting in Berlin, Germany. The presentation includes results from Abivax’s Phase 3 ABTECT 8-Week Induction Trials investigating obefazimod for the treatment of moderate-to-severely active ulcerative colitis, including previously reported findings and additional safety data at week 8.