B-FREE Chronic Babesiosis Study

• Company engaged patients diagnosed with chronic babesiosis via social media in a nationwide naming competition
• A $5K donation from the Company was split between ILADEF and GLA to recognize the winning name
• B-FREE, a Phase 2 trial, will commence in early November and run for approximately 12 months
  

WASHINGTON, Oct. 09, 2025 (GLOBE NEWSWIRE) --  60 Degrees Pharmaceuticals, Inc. (NASDAQ: SXTP; SXTPW) (“60 Degrees Pharma” or the “Company”), a pharmaceutical company focused on developing new medicines for vector-borne disease, announced today the name of its chronic babesiosis trial is the B-FREE Chronic Babesiosis Study.

The B-FREE study (NCT06656351), the first in the world to evaluate a potential new therapeutic for chronic babesiosis, will run for approximately 12 months. It is a Phase 2 open-label study that will evaluate the efficacy and safety of the ARAKODA regimen of tafenoquine over 90 days for resolution of severe fatigue, and parasite eradication in patients with chronic babesiosis, a potentially disabling condition carried by the same tick that spreads Lyme disease.

No U.S. Food and Drug Administration-approved drug or professional society-recommended treatment for chronic babesiosis is currently available.

"60 Degrees Pharma is so proud to be conducting this pioneering study of chronic babesiosis, a key plank in our plan to bring an FDA-approved babesiosis therapy to patients," said Company Chief Executive Officer, Geoffrey Dow. "We are grateful to the patients who participated in the B-FREE naming study, and to the distinguished scientific advisory boards and organizations we consulted for their assistance in drafting the study protocol. We also appreciate the staff at our contract research organization, Fast Track, and Mount Sinai for their valuable assistance in getting this first-of-its-kind study off the ground."

To identify the name for the B-FREE study, 60 Degrees engaged directly with the tick-borne disease patient community. A naming survey was shared through social media channels and distributed to patients and advocates, inviting them to contribute study names that that reflected the purpose of the trial. In turn, as a goodwill gesture, 60 Degrees Pharmaceuticals donated a total of $5,000 to the Global Lyme Alliance (GLA) and to the International Lyme and Associated Diseases Education Foundation (ILADEF), thus ensuring that patient input not only shaped the B-FREE study’s identity but also directly supported organizations that are advancing research and care.