University of Michigan study presentation at ANESTHESIOLOGY 2025 supports clinical and environmental benefits of End-tidal Control

GE HealthCare (Nasdaq: GEHC) today announced the presentation of findings from the largest real-world evidence study to-date on End-tidal Control anesthesia delivery* software conducted at the University of Michigan. The results demonstrated the environmental and clinical benefits of End-tidal Control software and were presented at ANESTHESIOLOGY 2025 taking place from October 10-14, in San Antonio, Texas.

End-tidal Control software supports the clinician in maintaining clinician-set targets for end-tidal anesthetic agent and oxygen concentrations with greater accuracy than manual adjustments.ⁱ End-tidal Control supports low-flow anesthesia,** which may help reduce the amount of anesthetic agent utilized, lowering greenhouse gas emissions and costs.ⁱⁱ

“Our research explored the usage and impact of End-tidal Control software in a real-world surgical setting,” said Principal Investigator Douglas Colquhoun, MB ChB, MPH, Assistant Professor of Anesthesiology at the University of Michigan.*** “The findings underscore End-tidal Control’s ability to reduce fresh gas flows, anesthetic agent usage and greenhouse gas emissions, which can improve resource utilization and environmental sustainability.”

The retrospective observational study conducted by the University of Michigan analyzed 14,730 general anesthesia cases of adults (18 years and older) to evaluate the usage patterns and impact of End-tidal Control in a hospital setting. Preliminary results showed:ⁱⁱⁱ

• End-tidal Control utilization in approximately half of the cases (50.5%) at the institution
• Reductions greater than 35% in fresh gas flow, sevoflurane utilization and carbon dioxide emissions during the maintenance phase of anesthesia**
• Consistent End-tidal Control usage, with the software active for 82.1% of the anesthesia maintenance phase

“Efficient and consistent care delivery is a top priority for healthcare systems today, as workforce shortages and increasingly complex patient needs continue to evolve,” said John Beard, MD, anesthesiologist and Chief Medical Officer of Patient Care Solutions at GE HealthCare. “Automation in anesthetic delivery can reduce variability in care and cognitive burden for clinicians, allowing them to focus on the most critical decisions for their patients. Preliminary findings from the University of Michigan study support the broad applicability of End-tidal Control in a large multisite academic medical center and the real-world results.”