Hemogenyx Pharmaceuticals PLC Announces Issue of Equity

THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION AS STIPULATED UNDER THE UK VERSION OF THE MARKET ABUSE REGULATION NO 596/2014 WHICH IS PART OF ENGLISH LAW BY VIRTUE OF THE EUROPEAN (WITHDRAWAL) ACT 2018, AS AMENDED. ON PUBLICATION OF THIS ANNOUNCEMENT VIA A REGULATORY INFORMATION SERVICE, THIS INFORMATION IS CONSIDERED TO BE IN THE PUBLIC DOMAIN.

Hemogenyx Pharmaceuticals plc

("Hemogenyx Pharmaceuticals" or the "Company")

Hemogenyx Secures £2,500,000 to continue its Phase 1 Clinical Trials

LONDON, UK / ACCESS Newswire / February 10, 2026 / Hemogenyx Pharmaceuticals plc (LSE:HEMO) is pleased to announce that it has raised £2,500,000 from a consortium of private investors through a direct subscription for 313,333 new ordinary shares in the Company at a price of £7.50 per share. The new investors will also receive a three year warrant to subscribe on a one-for-one basis for ordinary shares in the Company at £9 per share. Some of these investors taken part in earlier share subscriptions in recent months and we are grateful for their continuing support.

The net proceeds of this fundraise will be dedicated primarily to the continuation of the Phase I clinical trials for the Company's Chimeric Antigen Receptor T-cell therapy ("HG-CT-1"), aimed at treating relapsed/refractory acute myeloid leukemia ("R/R AML") both in adults and also now in children.

The Company received a positive recommendation from the independent Data Safety Monitoring Board ("DSMB") overseeing its ongoing Phase I clinical trial of HG-CT-1 in October 2025, supporting continuation of the trial with escalation to the next dose level in adults. In addition, the Company has received clearance from the U.S. Food and Drug Administration ("FDA") to initiate a Phase I clinical trial in pediatric patients aged 12-18 years.

In parallel, management has undertaken a concerted effort to significantly reduce the Company's burn rate. As part of this initiative, the Company outsourced the manufacturing of HG-CT-1 to a specialised external manufacturer, Made Scientific ("MADE"). The Company devoted substantial time to the technology transfer process and is currently in the final stages of this work, in preparation for the manufacture of HG-CT-1 for the first adult and pediatric patients. The next group of adult patients will be treated with an increased dose while pediatric patients will receive the lowest dose of HG-CT-1 which is going to be the same as in the first group of adults.