Oculis to Present Privosegtor at Upcoming Clinical Trials at the Summit 2026

ZUG, Switzerland, June 11, 2026 – Oculis Holding AG (Nasdaq: OCS; XICE: OCS) (“Oculis” or the “Company”), a global biopharmaceutical company focused on breakthrough innovations to address significant unmet medical needs in neuro-ophthalmology and ophthalmology, today announced an upcoming presentation at Clinical Trials at the Summit 2026, taking place on June 12-13, 2026, in Las Vegas, Nevada.

Oculis is a proud sponsor of Clinical Trials at the Summit 2026, which brings together experts from around the world to discuss ongoing clinical trials and the latest data, all with the goal of achieving advances in vitreoretinal care.

Details of Oculis’ presentation are as follows:

Clinical Trials at the Summit 2026:

• Privosegtor in Optic Neuritis: From Discovery to PIONEER Registrational Trials
  Presenter: Riad Sherif, M.D., Chief Executive Officer
  Date/Time: Saturday, June 13, 2026; 5:52 PM PDT

The presentation will highlight the development journey of Privosegtor, a peptoid small molecule that can cross both the blood-brain and retinal barriers and has the potential to become the first neuroprotective therapy for optic neuritis (ON), with potential broad applicability in other neuro-ophthalmic and neurological diseases. Following the successful Phase 2 ACUITY trial and the granting of Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA) for ON and PRIME (PRIority MEdicines) designation from the European Medicines Agency (EMA), Oculis is advancing the PIONEER registrational program for Privosegtor in optic neuropathies, with the PIONEER-1 trial in optic neuritis.

“Privosegtor is advancing through our PIONEER registrational program, offering the potential to address significant unmet medical needs in optic neuritis and other optic neuropathies where there are currently no approved neuroprotective therapies to prevent visual impairment,” said Riad Sherif, M.D., Chief Executive Officer of Oculis. “Our progress is supported by encouraging Phase 2 ACUITY data and key regulatory milestones, including Breakthrough Therapy and PRIME designations, and an FDA Special Protocol Assessment for PIONEER-1, which we believe support our strategic direction. We look forward to discussing the PIONEER program at Clinical Trials at the Summit as we navigate late-stage development with the aim of delivering potential transformative new options for patients.”

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