Publication of Idorsia's prospectus relating to the listing of Idorsia Ltd on SIX Swiss Exchange

Actelion Pharmaceuticals Ltd / Publication of Idorsia's prospectus relating to the listing of Idorsia Ltd on SIX Swiss Exchange . Processed and transmitted by Nasdaq Corporate Solutions. The issuer is solely responsible for the content of this announcement.

ALLSCHWIL/BASEL, SWITZERLAND - 09 June 2017 - Actelion Ltd (SIX:ATLN) today published the listing prospectus relating to the listing of Idorsia shares on SIX Swiss Exchange. With the tender offer for all publicly held shares of Actelion Ltd by Janssen Holding GmbH, a Swiss subsidiary of Johnson & Johnson (J&J) for Actelion on track for completion, it is expected that the settlement of the tender offer by J&J will take place on 16 June 2017. The demerger distribution, approved by the General Meeting of Actelion Shareholders held on 5 April 2017, will take place concurrently, whereby all Actelion shareholders (whether they tendered their shares or not) will receive one Idorsia share per each Actelion share held on 13 June 2017. It is expected that Idorsia shares will be listed and commence trading on SIX Swiss Exchange on 16 June 2017.

About Idorsia Ltd
Idorsia will be an independent biopharmaceutical company specialized in the discovery and development of small molecules to meet significant unmet medical needs. Idorsia will have a diverse clinical development pipeline comprising several compounds being investigated in multiple therapeutic areas, including central nervous system disorders, cardiovascular disorders, immunological disorders and orphan diseases. Idorsia will inherit Actelion's established and validated drug discovery engine and a strong cross-section of its development organization. Idorsia's pipeline will continue to be developed by selected members of Actelion's development organization who joined Idorsia.

Headquartered in Allschwil, Switzerland, Idorsia was incorporated on 2 March 2017 and will employ over 600 employees.

Idorsia's key strengths lie in the unique combination of:

• Skills: An experienced team comprising over 600 employees, with a proven track record of successfully bringing drug candidates to market
• Products: Ownership of a clinical pipeline of drug candidates in different areas of medicine where patients' needs are not fully met with existing therapies
• Assets: State-of-the-art facilities
• Cash: Financing with CHF 1 billion in cash. Additionally, Cilag, a subsidiary of Johnson & Johnson, will provide Idorsia with a CHF Credit Facility equivalent to USD 250 million

Idorsia's development pipeline