NeuBase Announces Formation of Gene Editing Advisory Board - Seite 2

James Coull, Ph.D.

Dr. Coull has 35 years of experience as a successful entrepreneur and builder of life science companies. He began his career at Millipore Corporation where he supervised teams of scientists working on the development of new methods and chemistries for synthesis and analysis of DNA, peptides and proteins. He then co-founded and was Vice President R&D at Boston Probes, Inc., where he spearheaded the development of its core PNA technology resulting in probe-based tests to identify pathogenic micro-organisms, genetic mutations and cancers, and which was acquired by Applied Biosystems. Dr. Coull has served as CTO of Ensemble Discovery, CTO and VP Business Development of AdvanDx, and CEO of PNA Innovations. He is currently a scientific and business consultant to various private and public life science companies. A pioneer of many innovative techniques, Jim is an inventor who is listed on more than 40 issued US patents and has published numerous peer-reviewed scientific articles. He holds a BSc in Chemistry from Colby College (1980) and received his Ph.D. in Biochemistry from Purdue University (1986).

Steven Dowdy, Ph.D.

Dr. Dowdy is a cancer biologist, specializing in the development of RNA therapeutics and in understanding cell cycle controls. He is a professor of cellular and molecular medicine at the University of California San Diego, School of Medicine, where his research focuses on the delivery of RNA therapeutics into cells, including the chemistry of developing endosomal escape technologies. Dr. Dowdy is a past member of the board of directors of the Oligonucleotide Therapeutics Society and consults extensively for biotechnology and pharmaceutical companies.

Peter Nielsen, Ph.D.

Dr. Nielsen is a leading expert in gene targeting, RNA interference and chemical replication and translation and was one of the inventors of PNAs in 1991. He is currently a professor at the University of Copenhagen, where his lab focuses on PNAs in regard to drug discovery, gene targeting, antisense principles, cellular and in vivo delivery, and administration of biopharmaceuticals. He is the co-author of more than 400 scientific papers and reviews, editor of 6 books, inventor on over 20 patents and patent applications, and he serves on the advisory board of four scientific journals, one of which he is section editor. In addition to his esteemed academic career, Dr. Nielsen is the co-founder of two biotechnology companies: PNA Diagnostics A/S, which was acquired by Boehringer Mannheim, and Pantheco A/S, which merged to form Santaris A/S and was subsequently acquired by Roche. Dr. Nielsen is a member of EMBO and the Danish Academy of Technical Sciences. Dr. Nielsen has been recognized for his seminal contributions to science by earning the Novo Nordic Foundation Prize (1997), the Lundbeck Foundation Prize (1997), and the InstitutCurie Jeanne Loubaresse Prize (Paris/France) (2002).