ProPhase Labs Teams up with Certis Oncology to Accelerate Development of Novel Linebacker Compound

Garden City, NY, Aug. 03, 2023 (GLOBE NEWSWIRE) -- ProPhase Labs, Inc. (NASDAQ: PRPH) (“ProPhase”), a next generation biotech, genomics, therapeutics and diagnostics company, today provided an update regarding its progress and development strategy for Linebacker-1 (LB-1), a small molecule, multi-kinase inhibitor that is being developed by the Company’s wholly owned subsidiary, ProPhase BioPharma, Inc. (“PBIO”), as a potential safer, more efficacious oncology therapy wholly unlike standard chemotherapeutic agents.

“ProPhase Labs continues to act as a disruptor in the therapeutic development space by employing only the most advanced, cutting-edge technology in the pursuit of clinical benefit and program success,” commented developmental lead Dr. Matt Halpert Ph.D. “Long gone are the days of blind experimentation with the hopes of achieving promising results.. We have entered an era in which if you are not at the forefront of high throughput analysis and technology for therapeutical development, you are not in therapeutical development.” With that mindset, ProPhase Labs has joined forces with Certis Oncology to use one-of-a-kind, robust, machine learning technology to exponentially improve the chances of successful development in the oncological therapeutic space.

“We have tested the novel Linebacker compound against hundreds of cancers and thousands of pathways, but will continue testing to the extent we believe useful data may be obtainable,” says Ted Karkus, CEO of ProPhase Labs. “By further mining all existing data sets, we are able to cross-reference genetic signatures, signaling pathways, and Linebacker responsiveness with Artificial Intelligence (AI), which we believe will greatly assist us in honing in on the most likely cancers and pathways that may be inhibited by Linebacker in the big picture.”

“Using Certis’s proprietary technology, CertisAI Predictive Oncology Intelligence, we determined that Linebacker may be effective against several types of cancer, but importantly not all cancers,” Dr. Halpert continued. “Selectivity is good, and being able to determine now what is most likely to be clinically relevant only improves the overall odds of success.” ProPhase intends to continue to line up AI-generated information with sound medical and scientific insights from experienced players to further guide development towards a regulatory pathway with lower barriers to entry and severe need in the clinic.