Editas Medicine to Present Clinical Data from the RUBY and EdiTHAL Trials of EDIT-301 at the ASH 2023 Annual Meeting and in a Company-sponsored Webinar

Company to host a webinar to discuss EDIT-301 clinical data on Monday, December 11, at 1:00 p.m. ET

Dr. Rabi Hanna from Cleveland Clinic Children’s to present EDIT-301 clinical data at ASH on Monday, December 11

CAMBRIDGE, Mass., Nov. 02, 2023 (GLOBE NEWSWIRE) -- Editas Medicine, Inc. (Nasdaq: EDIT), a clinical-stage genome editing company, today announced that a scientific abstract detailing safety and efficacy clinical data from the RUBY trial of EDIT-301 in patients with severe sickle cell disease and from the EdiTHAL trial of EDIT-301 in patients with transfusion-dependent beta thalassemia has been accepted for a poster presentation at the 65^th American Society of Hematology (ASH) Annual Meeting and Exposition being held December 9-12, 2023, in San Diego, CA, and online.

Editas Medicine will also host a Company-sponsored webinar on Monday, December 11, at 1:00 p.m. ET to discuss the RUBY and EdiTHAL clinical data.

Key data from patients treated in the RUBY trial and in the EdiTHAL trial will be shared, including:

• RUBY
  • Clinical data on 11 patients, including two patients with at least 12 months follow-up and an additional four patients with at least five months follow-up.
  • Efficacy data, including total hemoglobin, fetal hemoglobin, and vaso-occlusive events, or VOEs.
  • Safety data, including neutrophil and platelet engraftment.

• EdiTHAL
  • Clinical data on six patients, including at least five months data from the first two patients treated.
  • Efficacy data, including total hemoglobin and fetal hemoglobin.
  • Safety data, including neutrophil and platelet engraftment. 

“We are making significant progress with EDIT-301, and we look forward to sharing clinical data, including additional data collected since the submission of the abstract, from the RUBY and EdiTHAL trials next month at the American Society of Hematology Annual Meeting and in a Company-sponsored webinar. This data further supports our belief that EDIT-301 has the potential to be a clinically differentiated, one-time, durable medicine that can provide life-changing clinical benefits to patients,” Baisong Mei, M.D., Ph.D., Senior Vice President and Chief Medical Officer, Editas Medicine. “I would like to thank the participants, their families and caregivers, clinicians, and colleagues at collaborating institutions that contribute to the RUBY and EdiTHAL trials.”