UPDATE – Telomir Pharmaceuticals Announces Collaboration with Argenta to Study Osteoarthritis in Canines

Study to determine the efficacy of Telomir-1 on mitigating the clinical signs of osteoarthritis and other age-related diseases

This study is believed to be the first and only known study focused on reversing aging in canines

BALTIMORE, March 29, 2024 (GLOBE NEWSWIRE) -- Telomir Pharmaceuticals, Inc. (Nasdaq:TELO) (“Telomir” or the “Company”), a pre-clinical-stage pharmaceutical company focused on the development and commercialization of Telomir-1 as the first novel small molecule to lengthen the DNA’s protective telomere caps in order to potentially address age-related conditions, today announced that Telomir and global animal health contract research, development and manufacturing organisation Argenta have agreed to begin a three to six-months study on the efficacy of Telomir-1 as a treatment for osteoarthritis and other diseases of aging in canines. 

The study will evaluate the efficacy of Telomir-1 for mitigating the progression of osteoarthritis based on symptomatic, radiographic, gross pathologic and histopathologic evaluations. In addition, Telomir believes that this study could be used as part of its pre-clinicial program for eventually evaluating Telomir-1 in humans.

It is estimated that nearly 18 million canines in the United States are affected by osteoarthritis. Of those, only one third of the afflicted canines have a confirmed diagnosis and are being treated for the disease. Current treatments only address the symptoms of osteoarthritis, using behavioral therapies like weight management and pain medications such as NSAIDs and injectables.

“Osteoarthritis is the most common ailment in canines yet there are currently no treatments that combat the disease. As with human osteoarthritis, medical professionals are limited to treatments that only help manage the symptoms,” stated Chris Chapman, MD, Co-founder, Chairman, Chief Executive Officer and President of Telomir Pharmaceuticals. “Working with Argenta, a leading worldwide animal health research company, this study has the potential to demonstrate both the efficacy of Telomir-1 as well as a benign safety profile. We believe that Telomir-1 will offer an attractive treatment for this indication. Just as important, we believe that the results of this trial could be used to enable our submission of an Investigation New Drug Application to the FDA to study the potential effect of Telomir-1 on osteoarthritis in humans.”