ACTICOR BIOTECH

Topline Results of ACTISAVE Phase 2/3 Study in Stroke Treatment - Seite 2

Gilles AVENARD, Chief Executive Officer explains: "We will continue to investigate these results to better understand and evaluate consequences of this study with the investigators, the US and European regulatory agencies and our Board of Directors, to determine what further action should be taken. As previously announced, the Company is able to finance its operations until October 2024."

The ESOC oral presentation (abstract n°357) is entitled “ACTISAVE Clinical Trial: Efficacy and Safety of Glenzocimab on Top of Thrombolysis with or without Mechanical Thrombectomy” and will be held on May 15, 2024, at 11:00 am.

Glenzocimab is currently evaluated in two other clinical studies sponsored by academic teams:

• A Phase 2/3 GREEN study in stroke patients undergoing mechanical thrombectomy, with a futility analysis following the inclusion of the first 78 patients (30% of patients) expected in Q4 2024.

• A phase 2b LIBERATE study in the treatment of myocardial infarction, with final results expected in Q4 2025.

As reminder, the Company will publish its 2023 Full-Year Results and the URD on April 30, 2024, the General Meeting will take place on June 21, 2024.

About ACTICOR BIOTECH

Acticor Biotech is a clinical-stage biopharmaceutical company developing glenzocimab, an innovative drug for the treatment of cardiovascular emergencies, particularly ischemic stroke.

Positive results from the phase 1b/2a study, ACTIMIS, published in January 2024 in the Lancet Neurology (link to publication) confirmed the safety profile of glenzocimab and showed a reduction in mortality and intracerebral haemorrhage in the glenzocimab-treated group of stroke patients. These results were confirmed by a post-hoc analysis of brain imaging at 0 and 24 hours using artificial intelligence (Brainomix, UK). This independent analysis confirmed the reduction in the number and volume of intracerebral lesions in patients treated with glenzocimab.

In July 2022, Acticor Biotech obtained "PRIME" status from the European Medicines Agency (EMA) for glenzocimab in the treatment of stroke. This designation enables the company to strengthen its interactions and obtain early dialogues with regulatory authorities.

Acticor Biotech is backed by a panel of European and international investors (Mediolanum farmaceutici, Karista, Go Capital, Newton Biocapital, CMS Medical Venture Investment (HK) Limited, A&B (HK) Limited, Anaxago, and the Armesa Foundation) and has been listed on Euronext Growth Paris since November 2021 (ISIN: FR0014005OJ5 - ALACT).

For further information, please visit: https://www.acticor-biotech.com/

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The Acticor Biotech Stock at the time of publication of the news with a raise of +2,39 % to 3,85EUR on Frankfurt stock exchange (24. April 2024, 09:15 Uhr).