Multiple Abstracts Highlighting Vir Biotechnology’s Latest Hepatitis Delta & B Data Accepted for Presentation at the EASL Congress 2024

Vir Biotechnology, Inc. (Nasdaq: VIR) today announced that three abstracts highlighting new data from the Company’s chronic hepatitis delta and chronic hepatitis B programs have been accepted for presentation at the annual meeting of the European Association for the Study of the Liver, EASL Congress 2024, taking place in Milan, Italy from June 5-8. This includes an oral presentation on June 8, which was originally accepted as a late-breaker poster, that will highlight the Company’s latest Phase 2 SOLSTICE trial data. The Company also plans to host an investor conference call on June 5 at 6:00 a.m. ET / 12:00 p.m. CEST to discuss the data.

The SOLSTICE trial (NCT05461170) is evaluating the safety, tolerability and efficacy of tobevibart and elebsiran for the treatment of people living with chronic hepatitis delta. The oral presentation will include data on participants who have reached 12 and 24 weeks of chronic suppressive treatment. The Company will also share 48-week treatment data on the efficacy and safety of tobevibart and elebsiran for the six participants that were previously reported on at the 2023 American Association for the Study of Liver Diseases (AASLD) The Liver Meeting. The Company is on track to report additional 24-week treatment data on all the approximately 60 SOLSTICE participants in the fourth quarter of 2024.

“Vir remains steadfast in its mission to develop a transformative chronic suppressive therapy for the estimated 12 million or more people living with chronic hepatitis delta. The accepted abstracts highlight the remarkable progress we have made and the potential for tobevibart and elebsiran to make a significant impact in addressing this critical unmet need,” said Carey Hwang, M.D., Ph.D., Vir’s Senior Vice President, Clinical Research and Interim Chief Medical Officer. “We look forward to sharing new data which will offer further insights into virologic response rates, ALT normalization, and durability of viral suppression.”

Presentation details are as follows:

Oral Presentation

• Title: Efficacy and safety of tobevibart (VIR-3434) alone or in combination with elebsiran (VIR-2218) in participants with chronic hepatitis delta virus infection: preliminary results from the phase 2 SOLSTICE trial in non-cirrhotic and compensated cirrhotic participants (OS-127)
  Session: Viral hepatitis B/D: Therapy
  Date: Saturday, June 8
  Time: 11:45 a.m. CEST (5:45 a.m. EDT)
  Presenter: Tarik Asselah, M.D., Ph.D., Professor of Hepatology at the Hôpital Beaujon, APHP, Clichy, France, and at the University of Paris, and Head of Viral Hepatitis at INSERM UMR1149, France

Poster Presentations