Cellceutix Provides Additional Insight Into Successful Phase 2 Trial for Treating Psoriasis

BEVERLY, MA--(Marketwired - May 26, 2016) -  Cellceutix Corporation (OTC: CTIX) (the "Company"), a clinical stage biopharmaceutical company developing innovative therapies with oncology, dermatology, antibiotic, and anti-inflammatory applications, today provides additional insight into the successfully completed Phase 2 trial of Prurisol as a new oral therapy for mild to moderate plaque psoriasis.

As disclosed on May 24, 2016 (http://cellceutix.com/cellceutix-phase-2-trial-of-prurisol-for-mild-to-moderate-psoriasis-meets-primary-endpoint/#sthash.s7T0r6y3.dpbs), the trial enrolled 115 patients with mild to moderate plaque psoriasis, graded at a score of 2 ("mild") or 3 ("moderate") on the 5-point Investigator's Global Assessment (IGA) scale. The IGA scale ranges from a score of 0 ("clear") to a score of 4 ("severe"). The 12-week trial was structured with four arms, three receiving different dosing regimens of oral Prurisol (50mg, 100mg, 200mg) and one placebo arm. The primary endpoint was a 2-point reduction in the IGA score at Day 84.

Complete details of the Prurisol trial can be found at: https://clinicaltrials.gov/ct2/show/NCT02494479?term=cellceutix&rank=2.

New Information: Greatest Efficacy Seen in Patients with Moderate Psoriasis

As previously released, the trial achieved its primary endpoint in patients treated with 200mg of oral Prurisol. Among patients participating in the study with the severest form of psoriasis, those having a baseline IGA score of 3 ("moderate"), the primary endpoint was met in 46.2% of patients who received Prurisol 200mg. This data was derived from analyses of all patients randomized across all 9 participating study sites.

Additional preliminary data analyses of secondary endpoints show patients who received any dose of Prurisol, regardless of the treatment arm, had a 1-point improvement (using the IGA scoring system) at a higher rate than that of patients in the placebo arm. This is another clear indication of the drug's efficacy. Increases in Prurisol's therapeutic response, upon evaluating patients at Day 56 (Week 8) and Day 84 (Week 12) of treatment, also were apparent in the Prurisol 200mg arm, suggesting an improving response over time.