Phio Pharmaceuticals Announces Upcoming Presentations at the 81st Annual Meeting of the Society for Investigative Dermatology (SID)

Phio’s lead clinical product candidate, PH-762, is the subject of three new dermatological posters

MARLBOROUGH, Mass., April 16, 2024 (GLOBE NEWSWIRE) -- Phio Pharmaceuticals Corp. (Nasdaq: PHIO), a clinical stage biotechnology company whose proprietary INTASYL siRNA gene silencing technology is designed to make immune cells more effective in killing tumor cells, today announced it is presenting new data about its lead clinical candidate, PH-762, an INTASYL compound. The data will be presented in three posters at the annual meeting of the Society for Investigative Dermatology (SID) on May 16^th in Dallas, Texas.

The titles of the three posters are:

• INTASYL Self-delivering RNAi: a Flexible Platform to Treat Dermatological Malignancies

• INTASYL PH-762: Intratumoral Immunotherapy Targeting PD-1

• A Dose-Escalation Study of Intratumoral PH-762 Targeting PD-1 For Cutaneous Carcinoma
  

PH-762 is currently being studied in a US clinical trial to assess safety and efficacy in specific skin cancers (NCT 06014086). This open-label Phase 1 clinical study is designed to evaluate the safety and tolerability of neoadjuvant use of intratumoral PH-762 in Stages 1, 2, and 4 cutaneous squamous cell carcinoma, Stage 4 melanoma, and Stage 4 Merkel cell carcinoma. Stages 1 and 2 cSCC represent 77% of all new cSCC cases annually.

Presentation Details are as follows:
1.	Title:	INTASYL self-delivering RNAi: A Flexible Platform to Treat Dermatological Malignancies
	Abstract Number:	575
	Session Title:	Pharmacology and Therapeutic Development
	Presenting Authors:	Melissa Maxwell, Mary Spellman
	Session Date/Time:	Thursday, May 16, 4:30-6:30pm
	Location:	Trinity Exhibit Hall
2.	Title:	INTASYL PH-762: Intratumoral immunotherapy targeting PD-1
	Abstract Number:	576
	Session Title:	Pharmacology and Therapeutic Development
	Presenting Authors:	Melissa Maxwell, Mary Spellman
	Session Date/Time:	Thursday, May 16, 4:30-6:30pm
	Location:	Trinity Exhibit Hall
3.	Title:	Intratumoral PH-762 targeting PD-1 for Cutaneous Carcinoma
	Abstract Number:	283
	Session Title:	Clinical Research - Interventional Research
	Presenting Authors:	Melissa Maxwell, Mary Spellman
	Session Date/Time:	Thursday, May 16, 4:30-6:30pm
	Location:	Trinity Exhibit Hall

About Phio Pharmaceuticals Corp.