Change in the number of votes relating to Biotie Therapies Corp.´s shares

Biotie Therapies Corp.          Stock Exchange Release    2 April 2012 at 3.15
p.m.

Change in the number of votes relating to Biotie Therapies Corp.´s shares

The Swiss subsidiary of Biotie Therapies Corp. ("Biotie" or the "Company"),
Biotie Therapies Holding AG (previously Synosia Therapeutics Holding AG) has
conveyed Biotie shares Biotie shares against consideration pursuant to the
option programs as follows:

March 2012   Total (5/2011- Options % of the total
3/2012) outstanding amount of
shares

 161,462  5,034,250  9,597,730 2.5

The conveyance of Biotie shares relates to the option plan of Synosia
Therapeutics Holding AG (currently Biotie Therapies Holding AG, "Synosia")
acquired by Biotie in February 2011. According to such Synosia share option
plan, options have been granted to employees, former directors and consultants.
In connection with the completion of the acquisition of Synosia, the option plan
was amended so that instead of shares in Synosia an aggregate maximum of
14,912,155 shares in Biotie may be subscribed based on the plan. Biotie issued
these 14,912,155 shares to its current subsidiary Synosia in connection with the
acquisition to be further conveyed to the option holders when they potentially
exercise their option rights in accordance with the terms and conditions of the
option program.

The conveyed shares previously held by the Company´s subsidiary have not carried
any voting rights. The parent company Biotie does not own any treasury shares.
The conveyance does not affect the number of registered shares.

After the conveyances the changes are as follows:

The increase of A total amount of The number of the The total number
vote of the Company voting rights: Company´s share held of registered
March 2012 by the Group shares
March 2012:

 161,462 377,716,552  9,877,905 387,594,457

Turku, 2 April 2012

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Biotie Therapies Corp.
tel. [phone]
e-mail: [e-mail]

DISTRIBUTION
NASDAQ OMX Helsinki Ltd
Main Media
www.biotie.com

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Source: Biotie Therapies Oyj via Thomson Reuters ONE
[HUG#1599405]

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