Shire plc

Data Show A Bleeding Episode Occurs Every Three to 15 Seconds in People Living With Hemophilia Worldwide

Zug, Switzerland (ots/PRNewswire) -

On World Hemophilia Day 2017, Shire challenges the community to
collectively improve global standards of care for rare bleeding
disorders

Shire plc (LSE: SHP, NASDAQ: SHPG), a leading biotechnology
company focused on serving individuals with rare diseases, joins the
global bleeding disorders community in honoring the 28th annual World
Hemophilia Day (WHD).[1] On this day, Shire highlights initial
findings from its estimate of the Global Annual Bleed Rate (GABR),
which shows a bleeding episode occurs every three to 15 seconds
worldwide, more than three times current global estimates.[2] These
findings build on existing data from the World Federation of
Hemophilia (WFH), which show only 25 percent of individuals living
with hemophilia worldwide receive proper diagnosis and care, only 8
percent of which receive prophylaxis or regular treatment to prevent
bleeds.[3],[4] This research reinforces Shire's ongoing commitment to
innovative data collection to improve global standards of care for
individuals living with rare bleeding disorders.

"As the global leader in hematology, we are committed to efforts,
such as estimating the GABR, that improve our understanding of the
global landscape for hemophilia and the true experience of those
living with this debilitating bleeding disorder," said Leonard
Valentino, M.D., Global Head of Hematology Medical Affairs, Shire.

Shire developed the GABR in collaboration with renowned hemophilia
institutions, including WFH. Our shared aim is to identify regions of
the world with the greatest need for improved diagnosis and care for
hemophilia patients. Together, we created a literature-based model to
estimate the GABR at both country and global levels. A full report of
the GABR model is expected to be published later in 2017.[2]

"Shire is proud to support the global hemophilia community in
honoring World Hemophilia Day," continued Valentino. "On this day and
every day, Shire is dedicated to supporting hemophilia patients
through advancing early diagnosis, prophylaxis, individualized
treatment options and innovative research and development efforts."

This year, Shire is embracing WFH's theme for World Hemophilia Day
of "Hear Their Voices" and joining its partners and local advocacy
organizations to raise awareness of those living with bleeding
disorders. Throughout the day and across the world, Shire employees
are wearing red to show our support for the community and holding
celebrations to acknowledge the voices and stories of those living