Newly Published Results Reveal a Significant Proportion of Early-Stage HR+ Breast Cancer Survivors May Be Over- or Undertreated Without Breast Cancer Index Genomic Testing - Seite 2

Patients and physicians included in this study are participants in the BCI Registry Study. The BCI Registry Study is a prospective, large-scale, multi-center study that investigates long-term clinical outcomes, decision impact and medication adherence in patients with early-stage HR+ breast cancer receiving BCI testing as part of routine clinical care. The study concluded with the enrollment of over 3,000 patients who will continue to be followed until 10 years from diagnosis. The current publication reports results assessing the impact of BCI on clinical decision-making regarding extended anti-estrogen therapy in the first 1,000 patients enrolled in the BCI Registry Study.

Cancer patients look to their oncology care teams as experts for guidance in recommending the most appropriate treatment plan tailored to their individual health and needs. Ultimately, the newly published findings reveal that when incorporated into routine clinical care, BCI has the potential to provide clinicians with greater confidence in their treatment recommendations, with 39% of providers saying they felt more confident in their recommendation for extended anti-estrogen therapy following BCI testing. Additionally, BCI testing led to 41% of patients feeling more comfortable with their treatment decisions and 45% changing their preference regarding an additional five years of anti-estrogen therapy.

“For over 35 years, Hologic has been developing diagnostic solutions that are rooted in science and backed by robust clinical data. Alongside our portfolio of Breast and Skeletal Health Solutions, I’m proud of how Hologic’s Diagnostic Solutions division, through Biotheranostics, continues to transform the breast cancer care continuum for women and providers,” said Jennifer Schneiders, Ph.D., President of Diagnostic Solutions at Hologic. “As more research is published, I’m thrilled to see the continued, impressive utility of the Breast Cancer Index test. As seen in the results of this study, for women with early-stage hormone receptor-positive breast cancer, this test has the potential to reinforce the importance of the medication they are taking — or to allow them to discontinue treatment without fear of reoccurrence.”