Omega Therapeutics Announces Two Poster Presentations at the American Association for Cancer Research Annual Meeting 2024

CAMBRIDGE, Mass., March 06, 2024 (GLOBE NEWSWIRE) -- Omega Therapeutics, Inc. (Nasdaq: OMGA) (“Omega”), a clinical-stage biotechnology company pioneering the development of a new class of programmable epigenomic mRNA medicines, today announced that it will present two posters at the American Association for Cancer Research (AACR) Annual Meeting 2024, taking place in San Diego, California, April 5 – 10, 2024. The first poster will feature preclinical data validating a novel method for evaluating epigenomic controller (EC) target engagement using noninvasive liquid biopsies. Additionally, the Company will present new preclinical data supporting a MYC-targeting EC approach in models of non-small cell lung cancer (NSCLC) resistant to EGFR inhibitors.

Details for the poster presentations are as follows:

Title: Detection and quantification of site-specific DNA methylation from liquid biopsies as a pharmacodynamic biomarker of OTX-2002, a novel MYC-targeting epigenomic controller
Abstract Number: 2417 
Session: Circulating Nucleic Acids 2
Date and Time: April 8, 2024, from 9:00 a.m. to 12:30 p.m. PT

Title: Targeted epigenomic control of MYC as a strategy to treat EGFR inhibitor-resistant NSCLC
Abstract Number: 1726
Session: Epigenetic Targets in Oncology
Date and Time: April 8, 2024, from 9:00 a.m. to 12:30 p.m. PT

The posters will be made available on the Omega website at https://omegatherapeutics.com/science/publications/ at the same time as the presentations.

About the OMEGA Platform

The OMEGA platform leverages the Company’s deep understanding of gene regulation, genomic architecture and epigenetic mechanisms to design programmable epigenomic mRNA medicines that precisely target and modulate gene expression at the pre-transcriptional level. Combining a biology-first approach and world-class data science capabilities with rational drug design and customized delivery, the OMEGA platform enables control of fundamental epigenetic processes to correct the root cause of disease by returning aberrant gene expression to a normal range. Omega’s investigational programmable mRNA medicines, epigenomic controllers, target specific genomic loci within insulated genomic domains with high specificity to durably tune single or multiple genes to treat and cure diseases through unprecedented precision epigenomic control.