Siga Technology Inc:
WKN: 919473
Valuation
The fundamental factors that we factor into our analysis and
valuation have considerably strengthened
for SIGA in recent weeks as a number of important developments took
place:
- SIGA-246 fully protected monkeys from the human smallpox virus
(variola virus) that it prevented
from becoming infective by blocking the action of a viral enzyme
that is necessary for the assembly
of an envelope protein (p37) without which the virus is unable to
get out of the host (invaded) cells.
As a result, the virus becomes trapped inside the cell and is
unable to spread to other cells; the virus is
no longer infective! This specific viral enzyme is also present in
the monkeypox virus against which
it also showed complete protection in monkeys even though monkeypox
is more lethal to monkeys
than the human smallpox. Moreover, the studies in monkeys confirmed
the results of earlier studies in
SIGA Technologies, Inc. Advent Financial, Inc
www.adventfinancialinc.com - 14 - November 22, 2006
rodents in which SIGA-246 fully protected rodents against all
varieties of the poxvirus that were
tested.
- SIGA-246 appeared safe and to be well tolerated in a Phase I
trial on healthy volunteers that was
completed in June 2006.
- The Company is now preparing to submit the Phase I trial results
to the FDA as part of seeking
authorization to proceed with the Phase III trials that are
necessary for obtaining the data for
statistical proof of efficacy and safety that is required by the
FDA.
- The Company has recently obtained close to $21 million in
additional funding for completing the
development of SIGA-246 and submitting an NDA for it to the
FDA.
Factoring the above developments into our valuation model for SIGA
and using conservative
assumptions, we now estimate at 80% the probability that it will be
approved in 2008 and will
generate revenues of $410 million and fully diluted EPS of $1.35 in
FY09.
Assuming this stock will have a P/E of 10 by the end of FY09, its
price will then be $13.50 (fully
diluted). To calculate a 12-month Price Target for SIGA, we
discounted back by two years its future
value of $13.50 in FY09 using an annual discount factor of 0.129
that combines a 3-year, risk-free
4.80 % Treasury yield (source: Bloomberg.com - October 20, 2006)
and a 100% - 80% or 20% risk
factor. The resulting 12-month Price Target is $10.20. Discounting
back by three years, we
calculate a risk-adjusted Present Value of $ 9.40 for this stock
that has traded in the $3.50-to-$4.50
range in recent weeks.
Conclusion
We believe that SIGA may begin selling its first product, the
smallpox antiviral SIGA-246 and
achieve EPS of $1.35 on revenues of $410 million in FY09.
We reiterate our Buy recommendation and our 12-month Price Target
of $10.20 for SIGA.
Future product pipeline
SIGA Technologies leveraging bioterrorism defense funding for Short
Term Growth and Long Term Value •5 Opportunities each with annual
market potential > $1 Billion
•Smallpox Antiviral (SIGA-246)
•Smallpox Vaccine (4th generation)
• Arenavirus Antivirals (SIGA-294)
•Other Category A Pathogen Countermeasures
•Traditional Human Health Products: •Antivirals, Antimicrobials,
and Vaccines
Chart Siga Technology
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