BioArctic and Eisai Present New Data Regarding BAN2401 at the Alzheimer's Association International Conference 2019 - Seite 2

Further, increased BAN2401 exposure measured by serum concentrations correlated with larger reductions of amyloid beta in the brain measured by PET.

"The data presented today further demonstrate the uniqueness of BAN2401 and the robustness of the positive Phase 2b data previously presented. We look forward to Eisai´s progression of the confirmatory Phase 3 study in patients with early Alzheimer's disease," said Gunilla Osswald, CEO of BioArctic.

BAN2401 is being studied by BioArctic's partner Eisai in a Phase 3 study in patients with early Alzheimer's disease to confirm the previously announced Phase 2b study results.

This release discusses investigational uses of an agent in development and is not intended to convey conclusions about efficacy or safety. There is no guarantee that any investigational uses of such product will successfully complete clinical development or gain health authority approval.

For more information, please contact:  

Gunilla Osswald, PhD, CEO, BioArctic AB
E-mail: [e-mail]
Telephone: [phone]

This information was submitted for publication at 7:00 a.m. CET on July 18, 2019.

Notes to editors

About BAN2401 

BAN2401 is a humanized monoclonal antibody that is the result of a strategic research alliance between BioArctic and Eisai. BAN2401 has a unique binding profile and selectively binds to and eliminates soluble, toxic amyloid beta aggregates (protofibrils and oligomers) that are thought to contribute to the neurodegenerative process in Alzheimer's disease. As such, BAN2401 has the potential to have an effect on the disease pathology and to slow down the progression of the disease. Eisai obtained the global rights to study, develop, manufacture and market BAN2401 for the treatment of Alzheimer's disease pursuant to an agreement concluded with BioArctic in December 2007. In March 2014, Eisai and Biogen entered into a joint development and commercialization agreement for BAN2401. Currently, a global confirmatory Phase 3 clinical study (Clarity AD) of BAN2401 in patients with early Alzheimer´s disease is underway. According to Eisai, the final readout of the primary endpoint of the study is targeted for 2022.