IGC Pharma Announces Collaboration to Integrate AI into Clinical Trials

IGC Pharma, Inc. ("IGC" or the "Company") (NYSE American: IGC) today announced an Artificial Intelligence (AI) collaboration with Los Andes University’s Center for Research and Training in Artificial Intelligence (“CINFONIA”). The partnership aims to leverage Generative AI (AI) to analyze variations in disease signatures among patients, enabling IGC Pharma to identify individuals more likely to respond to treatment and subsequently accelerate the delivery of treatments to patients.

CINFONIA is the Center for Research and Training in Artificial Intelligence led by Professor Pablo Arbelaez at the University of Los Andes Department of Biomedical Engineering. CINFONIA integrates academic excellence, ethical principles, and responsible research to fulfill its mission of transforming the world with Artificial Intelligence for the benefit of humanity.

IGC Pharma and CINFONIA jointly intend to develop and train deep learning algorithms based on state-of-the- art transformer architectures to predict the temporal progression of approximately 1,500 physiological and psychological variables for each patient enrolled in the IGC-AD1 Phase 2 clinical trial.

These variables encompass neuropsychiatric scales, blood pressure, diet, and more intricate elements such as genetic markers and over 100 other biomarkers. The team has become implementing a deep learning algorithm to develop an adversary-based optimization methodology to enable the interpretation of non-linear relationships between these input variables and treatment outcomes, like efficacy and adverse events. The strategic integration of AI is an essential initiative for IGC Pharma as the Company is pursuing five assets developed to target Alzheimer's disease. These assets include IGC-AD1, TGR-63, LMP, IGC-1C, and IGC-M3, which are in different stages of development.

Ram Mukunda, CEO of IGC Pharma, commented, “Often Alzheimer’s patients face years of uncertainty and delayed definitive diagnosis, potentially resulting in the worsening of their condition. The implications of AI integration are profound, as it can help reduce risk in costly clinical trials and potentially get medicine to Alzheimer’s patients faster. We believe this partnership provides IGC Pharma with a competitive advantage in the pharmaceutical industry as implementing AI algorithms may enable us to identify and understand previously unknown patterns in data sets. We eagerly anticipate showcasing our strategic approach at Biotech Showcase 2024 during JP Morgan Healthcare Week, spotlighting IGC Pharma's strides in AI development.”