Endo's Qwo (collagenase clostridium histolyticum-aaes) Data to Be Presented at The Aesthetic Meeting 2021

DUBLIN, April 29, 2021 /PRNewswire/ -- Endo International plc (NASDAQ: ENDP) announced today that data relevant to the use of Endo Aesthetics' Qwo (collagenase clostridium histolyticum-aaes), which received FDA approval in July 2020 for the treatment of moderate to severe cellulite in the buttocks of adult women, will be presented during The Aesthetic Meeting 2021.

This data will be highlighted in two oral presentations during the virtual and in-person meeting taking place in Miami, FL April 29–May 3, 2021.

• "Reduction in Dimple Volume in Women With Buttock Cellulite Treated With Collagenase Clostridium Histolyticum-aaes;" Lawrence Bass, M.D., medical director and founder, Bass Plastic Surgery, PLLC, and QWO clinical trial investigator; Sunday, May 2
• "Real-World Effectiveness and Safety of Collagenase Clostridium Histolyticum-aaes Injections for the Treatment of Thigh Cellulite in Women: An Interim Analysis;" Sachin Shridharani, M.D., F.A.C.S., founder, LUXURGERY, and QWO clinical trial investigator; Sunday, May 2

QWO will also be discussed during The Aesthetic Meeting's well-respected Premier Global Hot Topics program on Friday, April 30.

INDICATION
QWO is indicated for the treatment of moderate to severe cellulite in the buttocks of adult women.

IMPORTANT SAFETY INFORMATION FOR QWO

CONTRAINDICATIONS
QWO is contraindicated in patients with a history of hypersensitivity to collagenase or to any of the excipients or the presence of infection at the injection sites.

WARNINGS AND PRECAUTIONS
Hypersensitivity Reactions
Serious hypersensitivity reactions including anaphylaxis have been reported with the use of collagenase clostridium histolyticum. If such a reaction occurs, further injection of QWO should be discontinued and appropriate medical therapy immediately instituted. Advise patients to seek immediate medical attention if they experience any symptoms of serious hypersensitivity reactions.

Injection Site Bruising
In clinical trials, 84% of subjects treated with QWO experienced injection site bruising. Subjects with coagulation disorders or using anticoagulant or antiplatelet medications (except those taking ≤150 mg aspirin daily) were excluded from participating in Trials 1 and 2.

QWO should be used with caution in patients with bleeding abnormalities or who are currently being treated with antiplatelet (except those taking ≤150 mg aspirin daily) or anticoagulant therapy.