Empower Clinics Accelerates Growth of Research and Clinical Trials Division with Signing of Two Additional Principal Investigators at First Site in Dallas, Texas

Addition Of Seasoned Principal Investigators At First SMO Site Dramatically Expands Access to Securing Multiple Research Projects Covering Numerous Specialties

VANCOUVER, BC / ACCESSWIRE / April 25, 2023 / EMPOWER CLINICS INC (CSE:EPW)(PINK:EPWCF) ("Empower" or the "Company") an integrated healthcare company with a developing research and clinical trials divisions is pleased to announce that its subsidiary EPW Curesearch LLC ("EPWC") has signed two new Research Services Agreements ("Research Agreement") with leading physicians and researchers who will act as the Principal Investigators (the "PI") supporting the provision of Pharmaceutical Research and Clinical Trials Services (the "Services") of the first site in Dallas, TX.

The addition of two additional PI's brings the active count of seasoned researchers to three and paves the way to conducting multiple research projects across a variety of specialties and disease states. PI's are practicing medical doctors who are specialists or internists with previous research and clinical trials experience that are integral to the success of the Clinical Trial process, including the establishment of Empower Clinics as a Site Management Organization ("SMO").

THE RESEARCH AND CLINICAL TRIALS BUSINESS CYCLE

In order for shareholders to better understand both the process and the critical role played by Empower within it, we have provided the following outline:

• Big Pharmaceutical companies conduct research and clinical trials on numerous disease states (the "Sponsor")
• Successful new drugs that get FDA or CE approval are worth billions to the Sponsor
• Sponsors typically outsource the management of research trials to Contract Research Organizations ("CRO")
• Specialized physicians referred to as Principal Investigators (PI's) become researchers at sites for the purpose of enrolling patients and supporting the trial
• The next segment of the industry is Site Management Organizations (SMO), and this is where Empower intends to operate. Specifically, Empower as an SMO enters into contracts with PI's, which in this case, is a large medical center with multiple PI's under contract
• Empower as the SMO liaises with both the CRO and the Sponsor to create a three-way contract for research and clinical trials with the Sponsor, CRO and the PI's
• Once the trial commences:
  • Patients enroll in a trial
  • They are seen by the PI on regular intervals
  • The PI gathers the required data
  • The data is assembled, de-identified and provided to the CRO and Sponsor
• As the SMO, Empower oversees the process of day-to-day patient management, site management, technology management and general oversight of the process
• Each month Empower as the SMO submits a detailed invoice to the CRO for patient management services and participation from the prior month

KEY METIRCS OF THE SITE MANAGEMENT ORGANIZATION