VBI Vaccines Announces PreHevbri is Now Available in the United Kingdom for the Prevention of Hepatitis B in Adults

VBI Vaccines Inc. (Nasdaq: VBIV) (VBI), a biopharmaceutical company driven by immunology in the pursuit of powerful prevention and treatment of disease, today announced that PreHevbri [Hepatitis B vaccine (recombinant, adsorbed)] is now available in the United Kingdom (“U.K.”) for active immunization against infection caused by all known subtypes of the hepatitis B virus (HBV) in adults. It can be expected that hepatitis D will also be prevented by immunization with PreHevbri as hepatitis D (caused by the delta agent) does not occur in the absence of hepatitis B infection. As part of the marketing and distribution partnership announced in September 2022, PreHevbri will be available in the U.K. through Valneva’s existing commercial infrastructure and distribution networks.

Jeff Baxter, President and CEO of VBI, commented: “We are delighted to announce the availability of PreHevbri in the U.K., marking the first European market launch of our 3-antigen hepatitis B vaccine, which builds upon the increasing momentum for use in the U.S. (available under the brand name PreHevbrio). We believe Valneva’s local commercial capabilities and relationships will be of significant value not only in this initial European launch, but also in the additional European markets where PreHevbri is expected to launch over the next several months.”

About Hepatitis B

Hepatitis B is one of the world’s most significant infectious disease threats with more than 290 million people infected globally. HBV infection is the leading cause of liver disease and, with current treatments, it is very difficult to cure, with many patients going on to develop liver cancers. An estimated 900,000 people die each year from complications of chronic HBV such as liver decompensation, cirrhosis, and hepatocellular carcinoma.

About PreHevbri [Hepatitis B vaccine (recombinant, adsorbed)]

PreHevbri is the only 3-antigen hepatitis B vaccine, comprised of the three hepatitis B surface antigens of the hepatitis B virus – S, pre-S1, and pre-S2. It is approved for use in the European Union/European Economic Area, United Kingdom, United States, Canada, and Israel. The brand names for this vaccine are: PreHevbri (EU/EEA/UK), PreHevbrio (US/Canada), and Sci-B-Vac (Israel).

Full European Summary of Product Characteristics for PreHevbri is available from the EMA website at www.ema.europa.eu.

Please visit www.PreHevbrio.com for U.S. Important Safety Information for PreHevbrio [Hepatitis B Vaccine (Recombinant)], or please see U.S. Full Prescribing Information.