NovAccess Global Partners with BCN Biosciences to Expand Immunotherapy Platform

Development Begins on Fourth Generation of Primary Drug TLR-AD1 Targeting CNS Tumors

Potential for Improved Outcomes for Cancer Patients in the $100 Billion a Year Immune Oncology Market

CLEVELAND, OH / ACCESSWIRE / July 27, 2023 / NovAccess Global Inc. (OTCQB:XSNX), a biomedical company developing novel immunotherapies for brain tumor patients, today announced the signing of a Letter of Intent (LOI) and formation of a partnership with BCN Biosciences to expand its immunotherapy platform. Utilizing BCN's small molecule drug BCN057, developed with support from the National Institutes of Health and in collaboration with the University of California Los Angeles (UCLA), NovAccess Global has begun the development of a fourth generation of its novel brain tumor immunotherapy TLR-AD1, targeting glioblastoma.

Awarded Orphan Drug Status by the U.S. Food and Drug Administration in 2022, TLR-AD1improves the ability of specialized blood cells, known as Dendritic Cells (DCs), to recognize tumors. These specialized blood cells then provide a ‘zip code' to the immune system improving its ability to seek out and destroy tumor cells in the body. While TLR-AD1 is the most advanced technology to enhance DC immunotherapy, a combination therapy leveraging BCN057 could further enhance DC tumor recognition as well as increase DC yield from patients' blood. The partnership between NovAccess Global and BCN provides a unique opportunity to further develop BCN057 in combination with TLR-AD1 to benefit patients with CNS cancer and potentially other cancer tumor types.

Based in Pasadena, CA and founded more than ten years ago, BCN Biosciences is a privately held oncology-focused drug development company leveraging long-term partnerships with NIH, Kansas University Medical Center, and UCLA. BCN has a portfolio of drug assets focusing on novel cancer targets and therapies that affect how cancer cells evade the body's immune system. BCN is currently developing two classes of novel small molecule drugs that target the RAS signaling pathway, a key molecular switch in the development of malignancies, and improve patient response to current classes of immune oncology therapy.