NanoString Launches the CosMx 6,000 plex RNA Assay and Showcases Whole Transcriptome Imaging Capability

NanoString Technologies, Inc. (NASDAQ: NSTG), a leading provider of life science tools for discovery and translational research, today announced the commercial availability of the CosMx Human 6K Discovery Panel, the industry’s first single-cell spatial panel enabling research scientists to measure over 6,000 RNA targets, representing nearly every human biological pathway. Building on this breakthrough product developed for the CosMx Spatial Molecular Imager (SMI), NanoString and independent researchers will also highlight recently achieved whole transcriptome imaging capability - the pinnacle of spatial biology - at the Advances in Genome Biology and Technology (AGBT) General Meeting, February 5-8 in Orlando, Florida.

Under the banner, “Plex YES!”, a theme inspired by customer reactions to the high plex CosMx Human 6K Discovery Panel, NanoString team members and early access researchers will highlight the CosMx SMI’s expanded capabilities with the official product launch at the annual AGBT meeting. These will include showcasing superior cell segmentation, genomic breadth, and capacity to profile genes across nearly every biological pathway and over 400 ligand-receptor pairs.

With the recently announced achievement of the whole transcriptome prototype panel on the CosMx SMI, researchers can now analyze almost 19,000 genes at true single-cell and subcellular resolution. Dr. Miranda Orr of Wake Forest University School of Medicine, Dr. Holger Heyn of Centro Nacional de Análisis Genómico, and Dennis Hua Gong of Massachusetts General Hospital and Harvard University will present novel research representing the first studies powered by whole transcriptome imaging.

"The CosMx Whole Transcriptome Panel is the ultimate tool for spatial biology; it resulted in new discoveries on my first run. I know I’m getting the maximum amount of data possible from precious tissue samples. It eliminates the tradeoff between resolution and plex," said Miranda Orr, Ph.D., of Wake Forest University School of Medicine. Following early access to the product, Dr. Orr observed, "The panel is advancing the understanding of senescent cells and unraveling the genomic signatures underlying their role in Alzheimer's Disease.”