Axsome Therapeutics Highlights Innovative Neuroscience Portfolio at the American Academy of Neurology (AAN) 2024 Annual Meeting

AXS-05 in Alzheimer’s disease agitation data featured in oral plenary session

New data for AXS-07 in migraine demonstrating efficacy in pooled analysis

Presentations on cognitive and wake promoting effects of solriamfetol

NEW YORK, April 15, 2024 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders, today announced presentations highlighting its innovative psychiatry and neurology pipeline at the American Academy of Neurology (AAN) 2024 annual meeting, being held April 13-18, 2024, in Denver, Colorado. The presentations include an oral presentation during the Clinical Trials Plenary Session of data from the ACCORD Phase 3 trial of AXS-05 in Alzheimer’s disease agitation (ADA). Presentations related to the AXS-07 clinical program in migraine include new pooled efficacy data from the MOMENTUM and INTERCEPT Phase 3 trials. Additionally, there will be data presentations on cognition and sleep from the solriamfetol clinical program.

Details for the presentations are as follows:

Alzheimer’s Disease Agitation

Title: Efficacy and Safety Of AXS-05 in Agitation Associated with Alzheimer’s Disease: Results From ACCORD, a Phase 3, Double-Blind, Placebo-Controlled, Relapse Prevention Trial
Presentation Date and Time: Tuesday, April 16 from 9:15 a.m. to 11:30 a.m. Mountain Time
Lead Author: Anton P. Porsteinsson, MD, William B. and Sheila Konar Professor of Psychiatry at the University of Rochester, School of Medicine and Dentistry
Session Name: PL5: Clinical Trials Plenary Session
Program Number: PL5.005

Migraine

Title: Combined Efficacy and Safety of AXS-07 (MOSEIC^TM Meloxicam and Rizatriptan) in Two Phase 3 Clinical Trials
Presentation Date and Time: Tuesday, April 16 from 11:45 a.m. to 12:45 p.m. Mountain Time
Lead Author: Stewert Tepper, MD, Professor of Neurology at the Geisel School of Medicine at Dartmouth
Session Name: P7: Headache: Therapeutics 2
Program Number: P7.002

Title: EMERGE Study: An Open-label Evaluation of the Efficacy and Safety of AXS-07 (MoSEIC meloxicam-rizatriptan) for Migraine in Adults with Prior Inadequate Response to an Oral CGRP Inhibitor
Presentation Date and Time: Tuesday, April 16 from 8 a.m. to 9 a.m. Mountain Time
Lead Author: Peter McAllister, MD, Director of the New England Center for Neurology and Headache
Session Name: P6: Headache: Therapeutics 1
Program Number: P6.006

Cognition

Title: Solriamfetol Improves Cognitive Performance in Preclinical Models of Sleep Apnea and in a Randomized Placebo-controlled Study of Sleep Apnea Participants (SHARP)