Verrica Pharmaceuticals Announces Presentation of Positive Data from New Pooled Analysis of Phase 3 CAMP Trials of VP-102

- Analysis suggested statistically significantly higher lesion clearance with VP-102 compared to vehicle in all regions of the body, including those deemed most sensitive -

- If approved, VP-102 will be marketed in the United States as YCANTH (cantharidin 0.7% Topical Solution), and would be the first FDA-approved treatment for molluscum -

WEST CHESTER, Pa., Jan. 18, 2020 (GLOBE NEWSWIRE) -- Verrica Pharmaceuticals Inc. (“Verrica”) (Nasdaq: VRCA), a dermatology therapeutics company developing medications for viral skin diseases requiring medical interventions, today announced the presentation of positive data from a post-hoc pooled analysis of the pivotal Phase 3 CAMP trials evaluating the safety and efficacy of VP-102 (cantharidin 0.7% topical solution), Verrica’s lead product candidate for the treatment of molluscum contagiosum (molluscum). The new analysis showed that the percentage of patients with complete clearance of all lesions was statistically significantly higher in the VP-102 group than vehicle, across all body regions. Results from this analysis are being presented in a poster on January 18^th-22^nd at the 17th Annual Winter Clinical Dermatology Conference in Kohala Coast, Hawaii.

“The results of this study are important, as they suggest that this investigational molluscum treatment can potentially bring about complete clearance, regardless of where on the body the lesion is located,” said Lawrence Eichenfield, MD, Chief of Pediatric and Adolescent Dermatology, Rady Children’s Hospital, San Diego, CA, and principal investigator of the VP-102 Phase 3 molluscum program. “If approved, VP-102 may potentially be an important option for physicians, as they can have the option to treat even the most sensitive areas, including the groin, head, and neck.”

In this analysis of the CAMP studies, the intent-to-treat (ITT) patient population had molluscum lesions in specific areas at baseline, including: head/neck (n=77 VP-102, n=53 vehicle); chest/abdomen (n=142, 118); back/buttocks (n=117, 91); groin (n=28, 25); upper extremities (n=179, 131); and lower extremities (n=186, 141). Efficacy was measured by the percentage of subjects with complete clearance of lesions in each location by visit. Data demonstrated a statistically significantly greater percentage of complete lesion clearance by the end of the study (Day 84) across all body regions analyzed among patients receiving VP-102, as compared to vehicle. Specific results showed: