Amarin Provides Update on VAZKEPA (Icosapent Ethyl) Intellectual Property Portfolio in Europe

Company’s IP Protection for VAZKEPA in Europe Now Extended Into 2039

DUBLIN, Ireland and BRIDGEWATER, N.J., April 03, 2024 (GLOBE NEWSWIRE) -- Amarin Corporation plc (NASDAQ:AMRN) today announced that the Company received a Decision to Grant from the European Patent Office (EPO) for a new patent covering VAZKEPA (icosapent ethyl) that will extend VAZKEPA exclusivity eight additional years into 2039. In addition, the Company recently achieved success defending a separate European VAZKEPA patent from third-party opposition within the EPO. Collectively, these patents cover both the protocol and results from the landmark REDUCE-IT outcomes study, providing an extended and strengthened exclusivity position for VAZKEPA within the Company’s European market.

“Today’s announcement extends the commercial runway for VAZKEPA in Europe by eight additional years, which enhances the potential impact that this product can have for patients and the growth potential for VAZKEPA across the continent,” said Patrick Holt, President & CEO, Amarin. “Moving forward, we will continue to rigorously defend our IP rights and explore any possibilities to strengthen Amarin’s patents and patent families around the world.”

Additional Details Regarding VAZKEPA IP Portfolio in Europe

The Decision to Grant from the EPO indicates a grant date of April 24, 2024, for a new Amarin patent containing claims covering VAZKEPA in Europe until April 2039. The claims of the 2039 patent arise from the pivotal REDUCE-IT cardiovascular outcomes trial relating to the use of VAZKEPA as an add-on treatment in adults being treated with a statin medicine who have high levels of triglycerides. Additional independent patent applications from this family remain pending, which when granted, will further reinforce VAZKEPA’s exclusivity in Europe until April 2039.

Additionally, in November 2023, Amarin successfully defended a separate patent containing claims covering VAZKEPA in Europe from third-party opposition. This patent expires in June 2033, and contains claims for reducing the risk of cardiovascular death and coronary revascularization based on the pivotal REDUCE-IT cardiovascular outcomes trial protocol. At the conclusion of that opposition, the EPO found all claims for Amarin’s 2033 VAZKEPA patent to be valid. Relatedly, the EPO recently allowed a separate pending patent application from this same 2033 patent family, which upon grant, will provide another VAZKEPA patent asset providing exclusivity in Europe until 2033.