Teva Announces Launch of its Generic Version of Canasa (mesalamine) Suppositories To Treat Adults with Active Ulcerative Proctitis (ulcerative rectal colitis), in the United States - Seite 2

Using mesalamine suppositories with certain other medicines may affect each other. Using mesalamine suppositories with other medicines can cause serious side effects.

Especially tell your doctor if you take nonsteroidal anti-inflammatory drugs (NSAIDS), or medicines that contain azathioprine or 6-mercaptopurine. Taking mesalamine with NSAIDS may cause kidney problems. Taking mesalamine with azathioprine or 6-mercaptopurine may cause blood problems. You doctor may do certain tests during treatment with mesalamine suppositories.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of mesalamine suppositories?

Mesalamine suppositories may cause serious side effects, including:

• Kidney problems. Your doctor will do certain tests before you start using mesalamine suppositories and during your treatment with mesalamine suppositories.

• Acute Intolerance Syndrome or Other Allergic Reactions. Some people who use mesalamine suppositories can have allergic type reactions, including “Acute Intolerance Syndrome.” Other allergic reactions can cause heart problems including an inflammation of the sac around the heart (pericarditis), blood problems, and problems with other organs in the body including the kidneys, liver and lungs. These problems usually happen in people who have had an allergic reaction to medicines containing sulfasalazine. Stop using mesalamine suppositories and tell your doctor right away if you get any of these symptoms: cramps, fever, stomach (abdominal) pain, headache, bloody diarrhea, rash, chest pain shortness of breath, decrease in the amount of urine, or fatigue.

• Liver problems. This can happen in people who have a history of liver problems and have taken other medicines that contain mesalamine. Tell your doctor right away if you get any of these symptoms while using mesalamine suppositories: yellowing of your eyes, flu-like symptoms, itchy skin, nausea or vomiting, or feeling very tired.

The most common side effects of mesalamine suppositories include dizziness, rectal pain, acne, fever, inflammation of the large intestine (colitis), and rash.

These are not all of the possible side effects of mesalamine suppositories.

Call your doctor for medical advice about side effects. You may report side effects to FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

For more information, please see accompanying full Prescribing Information. A copy may be requested from Teva U.S. Medical Information at 888-TEVA-USA (888-838-2872), [e-mail], or Teva’s Public Relations or Investor Relations contacts.