Sensorion to Host Key Opinion Leader Webinar on July 5, 2023; Confirms Upcoming Key Milestones

Regulatory News:

Sensorion (FR0012596468 – ALSEN) a pioneering clinical-stage biotechnology company which specializes in the development of novel therapies to restore, treat and prevent within the field of hearing loss disorders, announces it will host a Key Opinion Leader (KOL) webinar on Proof-of-Concept (POC) Phase 2a study preliminary results of SENS-401 for residual hearing preservation following cochlear implantation. Key data from the Phase 2a study will be reported in June.

The webinar will feature a presentation by KOL Professor Yann Nguyen M.D., Ph.D., ENT surgeon at the Otolaryngology Department at the Hospital Pitié Salpêtrière, Paris, France, who will provide an overview on the importance of residual hearing preservation and will present the surgical procedure developed for perilymph sampling.

Sensorion’s management team will provide an update on the preliminary results of the POC Phase 2a study of SENS-401 for the residual hearing preservation in patients who, due to having moderately severe to profound hearing impairment, are scheduled for cochlear implantation. The study has been developed with Sensorion’s partner, Cochlear Ltd., the global leader in implantable hearing devices.

A Q&A session will follow the formal presentations and the webinar will be subtitled live.

The Phase 2a trial is a multicentric, randomized, controlled, open-label trial aimed at evaluating the presence of SENS-401 in the cochlea (perilymph) after 7 days of twice-daily oral administration in adult participants prior to cochlear implantation due to moderately severe to profound hearing impairment. Patients start treatment with SENS-401 seven days before implantation and continue to receive SENS-401 for a further 42 days. The study also assesses a number of secondary endpoints, including the change of hearing threshold from baseline to the end of the study in the implanted ear at several frequencies.

Professor Yann Nguyen is an ENT professor at the Otolaryngology Department, at the Hospital Pitié Salpêtrière (Sorbonne Université, AP-HP), in Paris, France. His clinical activities are focused on middle ear surgery, cochlear implantation and lateral skull base surgery. He has a Ph.D. on “robot-based surgery for cochlear implantation”. He is now working on robotics at the Hearing Institute (Institut Pasteur/Inserm), and he leads the “RobOtol project”. Prof Nguyen’s goal is to design and evaluate surgical solutions from lab bench to operating room for hearing loss.