Allergy Therapeutics publishes encouraging new data for peanut allergy vaccine candidate in The Journal of Allergy and Clinical Immunology - Seite 3

Manuel Llobet, Chief Executive Officer of Allergy Therapeutics, commented: “The development of an effective and safe peanut allergy vaccine would be significant, offering huge and life-changing benefits to sufferers affected by this condition. The science behind allergy vaccination is incredibly difficult given the complexity of our immune systems and at Allergy Therapeutics we have been working on our peanut allergy vaccine for over three years. The results from this study are very promising and we’re excited to be progressing the vaccine into its first clinical trial in patients this summer.”

With manufacturing scale up of the product now underway and following agreement with several regulatory authorities on the clinical trial design a first-in-human phase I clinical trial of the candidate vaccine is due to begin.

The scientific publication in JACI, the most frequently cited allergy and immunology journal in the field, is titled Vaccine against peanut allergy based on engineered Virus-Like-Particles displaying single major peanut allergens and is available online at www.jacionline.org  

About Allergy Therapeutics
Allergy Therapeutics is an international commercial biotechnology company focussed on the treatment and diagnosis of allergic disorders, including aluminium free immunotherapy vaccines that have the potential to cure disease. The Group sells proprietary and third-party products from its subsidiaries in nine major European countries and via distribution agreements in an additional ten countries. Its broad pipeline of products in clinical development include vaccines for grass, tree and house dust mite, and peanut allergy vaccine in pre-clinical development. Adjuvant systems to boost performance of vaccines outside allergy are also in development.

Formed in 1999 out of SmithKline Beecham, Allergy Therapeutics is headquartered in Worthing, UK with more than 11,000m2 of state-of-the-art MHRA-approved manufacturing facilities and laboratories.  The Group, which has achieved double digit compound annual growth since formation, employs c.500 employees and is listed on the London Stock Exchange (AIM:AGY). For more information, please see www.allergytherapeutics.com

About the Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology publishes high-impact, cutting-edge clinical and translational research papers for allergists, immunologists, dermatologists, gastroenterologists, and other physicians and researchers interested in allergic diseases and clinical immunology. Articles cover such topics as asthma, food allergy, allergic rhinitis, atopic dermatitis, primary immune deficiencies, occupational and environmental allergy, and other allergic and immunologic diseases, and include clinical trials and mechanistic studies that report on novel therapies, insights into underlying mechanisms, and other discoveries that will inform our understanding of these diseases and ultimately improve the diagnosis and management of patients. With an impact factor of 14.110, the journal ranks 1st of 27 in the Allergy category and 6th of 158 in the Immunology category in the 2018 Journal Citation Reports, published by Clarivate.