Creation of novel medicines and better patient care for the future in an ecosystem - Seite 2

Orion extends its biopharmaceutical capabilities towards biologics (therapeutic proteins) and concomitantly starts systematically evaluate also other advanced treatment modalities. Potential target proteins of some diseases are unreachable for traditional small molecular drugs, which is shifting the pharmaceutical interest also towards large biologics  aimed at affecting the protein expression already in preliminary states. This is done in collaboration with the ecosystem technology partners professors Pasi Virta and Urpo Lamminmäki from university of Turku as well as Finnish biopharmaceutical and diagnostic companies having mutual interests. Professor Pasi Virta (Organic chemistry, University of Turku) and his team aim at finding new ways for chemical modifications of of antibodies to apply them as carriers for the tissue and cell-specific delivery of drugs, primarily of RNA-based therapeutics. Whereas university professor Urpo Lamminmäki (Biotechnology, University of Turku) and his team aim to expand the established recombinant antibody library technology to serve as a lead factory for therapeutics development. Both university groups educate top experts for drug development field being capable to act smoothly between the academic and industrial fields filling the obvious knowledge gap in this drug development field in Finland. Syrinx Bioanalytics aims to develop novel analytical methods for next generation oligonucleotides to be utilized for pharmacokinetic, immunogenicity and biological activity studies during drug development. Admescope develops novel ligand binding assay, drug-drug interaction models and analytical methodology for therapeutic large molecules. Inme collaborates with the University of Turku (Department of Biotechnology) in order to achieve new-generation high-sensitivity immunoassay for hormonal analyses. Forendo Pharma supports the ecosystem with its expertise.

The established New Modalities Ecosystems creates novel capabilities and expertise that can be expanded and utilized more broadly beyond the ecosystem providing competitive edge also for other companies in developing their business models and supporting their growth. 

Further information:
Professor Antti Haapalinna, Vice President, Research and Development
Global Head, Therapy Area Rare Diseases & 
Biologics, Biomarkers and New Modalities Global Function
Orion Corporation ORION PHARMA,
[e-mail] or  Mob. [phone]

Publisher:
Orion Corporation
Communications
Orionintie 1A, FI-02200 Espoo, Finland
www.orion.fi

About Orion
Orion is a globally operating Finnish pharmaceutical company - a builder of well-being. Orion develops, manufactures and markets human and veterinary pharmaceuticals and active pharmaceutical ingredients. The company is continuously developing new drugs and treatment methods. The core therapy areas of Orion's pharmaceutical R&D are central nervous system (CNS) disorders, oncology and respiratory diseases for which Orion develops inhaled Easyhaler pulmonary drugs. Orion's adjusted net sales in 2017 amounted to EUR 1,034 million and the company had about 3,200 employees. Orion's A and B shares are listed on Nasdaq Helsinki.

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Source: Orion Oyj via Globenewswire