Leading Peer-Reviewed Ophthalmic Journal Publishes Study on ImprimisRx’s Proprietary Klarity-C Drops

Multi-center Retrospective Study Demonstrates Statistically Significant Reduction in Signs and Symptoms of Dry Eye Disease

NASHVILLE, Tenn., May 17, 2021 (GLOBE NEWSWIRE) -- ImprimisRx, the nation’s leading ophthalmic-focused outsourcing facility and pharmaceutical compounding business and a wholly owned subsidiary of Harrow Health, Inc. (NASDAQ: HROW), today announced that a study of its Klarity-C Drops (cyclosporine 0.1% ophthalmic emulsion PF) has been published in the peer-reviewed journal, Clinical Ophthalmology.¹ Klarity-C is a compounded cyclosporine eye drop currently prescribed by thousands of doctors across the United States. The preservative-free drop contains an emulsion with chondroitin sulfate and the active ingredient cyclosporine 0.1%, which has long been used to improve tear quality.^2-4

“We’re pleased with the outstanding results of this multi-center retrospective study, which illuminate the clinical benefits that twice-daily treatment with our proprietary Klarity-C formulation may offer patients suffering from signs and symptoms of dry eye. More and more U.S. eyecare professionals are recognizing that Klarity-C is an important prescribing choice for the millions of patients suffering with the discomfort and dissatisfaction associated with many other treatment options,” said ImprimisRx President John Saharek. “We developed Klarity-C as an easy-to-use, preservative-free, affordable option that requires no insurance company prior authorizations, manufacturer coupons or rebate forms. We believe this study, performed by three renowned ophthalmologists with extensive dry eye disease pedigrees, supports the positive experiences of the many tens of thousands of patients who have been prescribed Klarity-C.”

Klarity-C is compounded in a 503B FDA-registered and inspected outsourcing facility and is protected by patents issued in the United States and abroad.

Summary of the Study
In this multi-center retrospective study of 50 adult patients (100 eyes), dry eye disease was defined as an ocular surface disease index (OSDI) score over 12 or a corneal staining grade over 1. All patients were treated with Klarity-C. At 3 months, mean OSDI scores improved significantly (38.19 vs 24.18, p < 0.001), as did the mean corneal staining grades (3.62 vs 2.20, p < 0.001). Based on OSDI scores, the number of patients with severe dry eye dropped from 31 to 10, and 17 reached the normal range. Eyes with corneal staining grades of 2 or 3 dropped from 21 to 8; 50 eyes had no corneal staining. No adverse events were observed.