bit.bio Announced as Inaugural Partner of Ginkgo Bioworks’ New Technology Network - Seite 2

Ginkgo is uniquely positioned to act as a “systems integrator” for the biotech ecosystem, offering customers a much more unified experience. As a platform company, Ginkgo makes customer-driven infrastructure investments and is incentivised to make its tools and capabilities available to customers. Ginkgo’s programs require the integration of both existing capabilities and new techniques and approaches. This approach to biology allows customers to access a range of technical approaches rather than feel constrained by the status quo.

Notes to Editors

About the Ginkgo Technology Network

Read the full press release on the Network, including all inaugural partners here https://www.ginkgobioworks.com/2024/02/28/ginkgo-technology-network-la ...

About bit.bio

bit.bio is a synthetic biology company focused on human cells that is advancing medicine (UN SDG9) and enabling curative treatments (UN SDG3). The company does this by industrialising the manufacture of human cells and making them more accessible. The company was spun out of the University of Cambridge in 2016 and has since raised approximately $200m from investors such as Arch Venture, Foresite Capital, Milky Way, Charles River Laboratories, National Resilience, Tencent, Verition Fund and Puhua Capital.

bit.bio’s opti-ox precision cell programming and manufacturing technology enables conversion of induced pluripotent stem cells (iPSCs) into any desired human cell type in a single step. This can be achieved within days and at industrial scale, while maintaining exceptional purity and unparalleled consistency.

Our discovery platform extends this approach to any desired cell type by identifying the transcription factor combinations that define cell states (including identity, cell subtype identity, maturity) using high throughput screens and advanced data analysis. We believe that opti-ox can revolutionise regenerative medicine similarly to how CRISPR is unlocking gene therapy.

bit.bio’s cell therapy pipeline, based on txCells, is focused on serious diseases that lack effective treatments. Our current therapeutic development areas include metabolism and endocrinology, immunology and neurology. Our lead candidate, bbHEP01 based on txHepatocytes, is in development as a treatment for patients suffering from acute liver failure (ALF) and acute-on-chronic liver failure (ACLF). Complementing our internal pipeline, we have a collaboration with BlueRock Therapeutics (a wholly owned independently operated subsidiary of Bayer AG) focused on regulatory T cell (Treg) based cell therapies.