Cellceutix's New Chief Operating Officer Dr. James Alexander Addresses Shareholders - Seite 2

"My extensive background in development of compounds for infectious diseases has spurred my excitement about Brilacidin and the whole defensin-mimetic franchise of Cellceutix; I have never seen anything similar. When Cellceutix acquired these novel assets at such a low price last year I had hoped that there might be a larger role for me at Cellcelutix eventually. That has indeed happened and at a time when we now have positive top-line data from the Phase 2b trial in Acute Bacterial Skin and Skin Structure Infections showing that a one-day treatment with Brilacidin -- a single dose -- produces results comparable to 7 days of daptomycin treatment. What I see -- and what I think many people still don't fully grasp -- is that Brilacidin is not just a potential blockbuster for the indication of ABSSSI, including infections caused by MRSA, but this trial provides proof-of-efficacy data for defensin-mimetics as a novel class of antimicrobials that may be used to treat a broad array of diseases and conditions with a very limited chance for drug resistance to develop. I don't believe the potential efficacy of defenisin-mimetics was ever questioned by the scientific community, it was rather whether there would be any safety concerns. The results of this completed Phase 2b study provide reassuring top-line safety data for Brilacidin. We plan to leverage the clinical data we now have for Brilacidin to move quickly into mid-stage trials, while concurrently seeking every expedited pathway of the Food and Drug Administration available. Brilacidin for oral mucositis is next in line, taking into account its anti-inflammatory and immunomodulatory activity, with diabetic foot infections and ocular and otic conditions next on the clinical docket for us. Moving forward, we are planning IND filings for defensin-mimetics with antifungal activity as well as activity against resistant Gram negative pathogens.

"With these things in mind, we think our shareholders will be pleased to know that we have filed an S-3 with the SEC to solidify our financial position for the years to come. Simply, we have plenty of cash on hand and available to us for our planned laboratory and clinical studies, but a shelf registration with a few year term affords us the opportunity to explore other future considerations that are immediately accretive to our corporate value, whether it is additional clinical trials or an acquisition. We're under no pressure to ever exercise the registration, but it is a prudent financial move to have additional cash available to us should a unique opportunity arise.