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VAXIL PROVIDES UPDATE ON PRECLINICAL EXPERIMENT - Seite 2

The response in the combination of all three peptides was less than expected, which we hypothesize may be due to the impurities of the one peptide (as explained above) or it may be as a result of dosage, both of which are being adjusted and analyzed in our current work.

The uniqueness of the platform is that Vaxil’s peptides have the potential distinct benefits of eliciting both a T cell (cellular) and B cell (humoral) immune response. We believe this broader immune response should be more effective as a preventive vaccine.

Vaxil has already begun the next set of experiments in our preclinical program to better understand the immune responses and determine dosing. Vaxil intends to perform additional experiments including assessing patient plasma, in vitro cytotoxicity, in vivo immunogenicity and ex vivo T cell proliferation and cytokine release.

 “We are excited to see this early validation of our modelling”, said David Goren, Vaxil’s Chairman and Chief Executive Officer, and continued to say “that given the need to vaccinate billions of people, the world will need multiple vaccination strategies to ensure success and meet the immense demand. We continue to be optimistic that we can play a role in this critical time of need.”

For more detailed results of this first vaccine candidate experiment, please see our presentation on our website vaxil-bio.com/Covid-19.

Dr. Applebaum has read and approved of the scientific disclosure in the news release.

The Company is not making any express or implied claims that it has developed a vaccine to treat COVID-19 (or SARS-CoV-2) at this time.

ABOUT VAXIL

Vaxil is an Israeli immunotherapy biotech company focused on its novel approach to targeting prominent cancer markers and infectious diseases. Its lead product ImMucin successfully completed a Phase 1/2 clinical trial in multiple myeloma and received orphan drug status from the FDA and EMA. The company continues to develop ImMucin and is also developing a tuberculosis vaccine / treatment that has demonstrated promising preliminary results with further preclinical evaluation underway at a top US academic and research institution. Additional indications and mAb candidates are under evaluation as immuno-oncology and infectious disease treatments alone and in combination with other treatments.